AC T10291
XX
ID T10291
XX
DT 05.03.2007 (created); sri.
CO Copyright (C), QIAGEN.
XX
FA TFEA-isoform1
XX
SY TFE3; TFEA.
XX
OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
XX
GE G004669 TFE3; HGNC: TFE3.
XX
CL C0012; bHLH-ZIP.
XX
SZ 575 AA; 61.5 kDa (cDNA) (calc.), 62-68 kDa (SDS)
XX
SQ MSHAAEPARDGVEASAEGPRAVFVLLEERRPADSAQLLSLNSLLPESGIVADIELENVLD
SQ PDSFYELKSQPLPLRSSLPISLQATPATPATLSASSSAGGSRTPAMSSSSSSRVLLRQQL
SQ MRAQAQEQERRERREQAAAAPFPSPAPASPAISVVGVSAGGHTLSRPPPAQVPREVLKVQ
SQ THLENPTRYHLQQARRQQVKQYLSTTLGPKLASQALTPPPGPASAQPLPAPEAAHTTGPT
SQ GSAPNSPMALLTIGSSSEKEIDDVIDEIISLESSYNDEMLSYLPGGTTGLQLPSTLPVSG
SQ NLLDVYSSQGVATPAITVSNSCPAELPNIKREISETEAKALLKERQKKDNHNLIERRRRF
SQ NINDRIKELGTLIPKSSDPEMRWNKGTILKASVDYIRKLQKEQQRSKDLESRQRSLEQAN
SQ RSLQLRIQELELQAQIHGLPVPPTPGLLSLATTSASDSLKPEQLDIEEEGRPGAATFHVG
SQ GGPAQNAPHQQPPAPPSDALLDLHFPSDHLGDLGDPFHLGLEDILMEEEEGVVGGLSGGA
SQ LSPLRAASDPLLSSVSPAVSKASSRRSSFSMEEES
XX
SC Swiss-Prot#P19532
XX
FT 137 193 
PS50888; HLH.
FT 140 193 
PF00010; Helix-loop-helix DNA-binding domain.
FT 145 198 
SM00353; finulus.
XX
IN T10289 MITF-M1; human, Homo sapiens.
XX
MX M01034 V$EBOX_Q6_01.
MX M03890 V$TFEA_Q6.
MX M01029 V$TFE_Q6.
XX
BS R38071.
BS R38070.
BS R63033.
BS R63035.
BS R37889.
BS R10079.
BS R04412.
BS R00853.
BS R10066.
XX
DR TRANSPATH: MO000102016.
DR EMBL: X51330;
DR UniProtKB: P19532;
XX
RN [1]; RE0000607.
RX PUBMED: 2338243.
RA Beckmann H., Su L.-K., Kadesch T.
RT TFE3: a helix-loop-helix protein that activates transcription through the immunoglobulin enhancer E3 motif
RL Genes Dev. 4:167-179 (1990).
RN [2]; RE0000701.
RX PUBMED: 2044953.
RA Beckmann H., Kadesch T.
RT The leucine zipper of TFE3 dictates helix-loop-helix dimerization specificity
RL Genes Dev. 5:1057-1066 (1991).
RN [3]; RE0003338.
RX PUBMED: 1465398.
RA Fisher D. E., Parent L. A., Sharp P. A.
RT Myc/Max and other helix-loop-helix/leucine zipper proteins bend DNA toward the minor groove
RL Proc. Natl. Acad. Sci. USA 89:11779-11783 (1992).
RN [4]; RE0025050.
RX PUBMED: 12748276.
RA Giangrande P. H., Hallstrom T. C., Tunyaplin C., Calame K., Nevins J. R.
RT Identification of E-box factor TFE3 as a functional partner for the E2F3 transcription factor.
RL Mol. Cell. Biol. 23:3707-3720 (2003).
RN [5]; RE0049462.
RX PUBMED: 15507434.
RA Miller A. J., Levy C., Davis I. J., Razin E., Fisher D. E.
RT Sumoylation of MITF and its related family members TFE3 and TFEB.
RL J. Biol. Chem. 280:146-155 (2005).
XX
//