TRANSFAC-Logo

TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN


AC T10758 XX ID T10758 XX DT 23.08.2007 (created); tgo. DT 03.09.2015 (updated); jmh. CO Copyright (C), QIAGEN. XX FA slug XX SY Neural Crest Transcription Factor SLUG; SLUGH; Zinc Finger Transcription Factor SLUG. XX OS human, Homo sapiens OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates XX GE G002941 SNAI2; HGNC: SNAI2. XX CL C0001; CH. XX SZ 268 AA; 30.0 kDa (cDNA) (calc.). XX SQ MPRSFLVKKHFNASKKPNYSELDTHTVIISPYLYESYSMPVIPQPEILSSGAYSPITVWT SQ TAAPFHAQLPNGLSPLSGYSSSLGRVSPPPPSDTSSKDHSGSESPISDEEERLQSKLSDP SQ HAIEAEKFQCNLCNKTYSTFSGLAKHKQLHCDAQSRKSFSCKYCDKEYVSLGALKMHIRT SQ HTLPCVCKICGKAFSRPWLLQGHIRTHTGEKPFSCPHCNRAFADRSNLRAHLQTHSDVKK SQ YQCKNCSKTFSRMSLLHKHEESGCCVAH XX SC translated from EMBL #AF042001 XX FT 128 150 zinc finger (C2H2-type) [1]. FT 128 150 PF00096; zf-C2H2. FT 128 150 SM00355; c2h2final6. FT 128 155 PS50157; ZINC_FINGER_C2H2_2. FT 159 181 zinc finger (C2H2-type) [1]. FT 159 181 PF00096; zf-C2H2. FT 159 181 SM00355; c2h2final6. FT 159 182 PS50157; ZINC_FINGER_C2H2_2. FT 185 207 zinc finger (C2H2-type) [1]. FT 185 207 PF00096; zf-C2H2. FT 185 207 SM00355; c2h2final6. FT 185 212 PS50157; ZINC_FINGER_C2H2_2. FT 213 235 zinc finger (C2H2-type) [1]. FT 213 235 PF00096; zf-C2H2. FT 213 235 SM00355; c2h2final6. FT 213 240 PS50157; ZINC_FINGER_C2H2_2. FT 241 264 PF00096; zf-C2H2. FT 241 268 PS50157; ZINC_FINGER_C2H2_2. FT 241 268 SM00355; c2h2final6. XX IN T00671 p53; human, Homo sapiens. XX MX M03565 V$SLUG_Q6. MX M07367 V$SLUG_Q6_01. MX M07394 V$SLUG_Q6_02. XX BS R34757. BS R37440. BS R37443. BS R67419. BS R71696. BS R31047. BS R37974. BS R37975. BS R68885. BS R68894. BS R68895. BS R68896. BS R68897. BS R66485. BS R69514. XX DR TRANSPATH: MO000112641. DR EMBL: AF042001; DR EMBL: AF084243; DR UniProtKB: O43623; XX RN [1]; RE0017410. RX PUBMED: 9721220. RA Cohen M. E., Yin M., Paznekas W. A., Schertzer M., Wood S., Jabs E. W. RT Human SLUG gene organization, expression, and chromosome map location on 8q RL Genomics 51:468-471 (1998). RN [2]; RE0017411. RX PUBMED: 10479723. RA Stegmann K., Boecker J., Kosan C., Ermert A., Kunz J., Koch M. C. RT Human transcription factor SLUG: mutation analysis in patients with neural tube defects and identification of a missense mutation (D119E) in the Slug subfamily-defining region RL Mutat. Res. 406:63-69 (1999). RN [3]; RE0017418. RX PUBMED: 9659933. RA Jiang R., Lan Y., Norton C. R., Sundberg J. P., Gridley T. RT The Slug gene is not essential for mesoderm or neural crest development in mice RL Dev. Biol. 198:277-285 (1998). RN [4]; RE0065166. RX PUBMED: 19448627. RA Wang S. P., Wang W. L., Chang Y. L., Wu C. T., Chao Y. C., Kao S. H., Yuan A., Lin C. W., Yang S. C., Chan W. K., Li K. C., Hong T. M., Yang P. C. RT p53 controls cancer cell invasion by inducing the MDM2-mediated degradation of Slug. RL Nat. Cell Biol. 11:694-704 (2009). XX //