AC T10758
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ID T10758
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DT 23.08.2007 (created); tgo.
DT 03.09.2015 (updated); jmh.
CO Copyright (C), QIAGEN.
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FA slug
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SY Neural Crest Transcription Factor SLUG; SLUGH; Zinc Finger Transcription Factor SLUG.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G002941 SNAI2; HGNC: SNAI2.
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CL C0001; CH.
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SZ 268 AA; 30.0 kDa (cDNA) (calc.).
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SQ MPRSFLVKKHFNASKKPNYSELDTHTVIISPYLYESYSMPVIPQPEILSSGAYSPITVWT
SQ TAAPFHAQLPNGLSPLSGYSSSLGRVSPPPPSDTSSKDHSGSESPISDEEERLQSKLSDP
SQ HAIEAEKFQCNLCNKTYSTFSGLAKHKQLHCDAQSRKSFSCKYCDKEYVSLGALKMHIRT
SQ HTLPCVCKICGKAFSRPWLLQGHIRTHTGEKPFSCPHCNRAFADRSNLRAHLQTHSDVKK
SQ YQCKNCSKTFSRMSLLHKHEESGCCVAH
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SC translated from EMBL #AF042001
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FT 128 150 
zinc finger (C2H2-type) [1].
FT 128 150 
PF00096; zf-C2H2.
FT 128 150 
SM00355; c2h2final6.
FT 128 155 
PS50157; ZINC_FINGER_C2H2_2.
FT 159 181 
zinc finger (C2H2-type) [1].
FT 159 181 
PF00096; zf-C2H2.
FT 159 181 
SM00355; c2h2final6.
FT 159 182 
PS50157; ZINC_FINGER_C2H2_2.
FT 185 207 
zinc finger (C2H2-type) [1].
FT 185 207 
PF00096; zf-C2H2.
FT 185 207 SM00355; c2h2final6.
FT 185 212 PS50157; ZINC_FINGER_C2H2_2.
FT 213 235 zinc finger (C2H2-type) [1].
FT 213 235 PF00096; zf-C2H2.
FT 213 235 SM00355; c2h2final6.
FT 213 240 PS50157; ZINC_FINGER_C2H2_2.
FT 241 264 PF00096; zf-C2H2.
FT 241 268 PS50157; ZINC_FINGER_C2H2_2.
FT 241 268 SM00355; c2h2final6.
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IN T00671 p53; human, Homo sapiens.
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MX M03565 V$SLUG_Q6.
MX M07367 V$SLUG_Q6_01.
MX M07394 V$SLUG_Q6_02.
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BS R34757.
BS R37440.
BS R37443.
BS R67419.
BS R71696.
BS R31047.
BS R37974.
BS R37975.
BS R68885.
BS R68894.
BS R68895.
BS R68896.
BS R68897.
BS R66485.
BS R69514.
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DR TRANSPATH: MO000112641.
DR EMBL: AF042001;
DR EMBL: AF084243;
DR UniProtKB: O43623;
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RN [1]; RE0017410.
RX PUBMED: 9721220.
RA Cohen M. E., Yin M., Paznekas W. A., Schertzer M., Wood S., Jabs E. W.
RT Human SLUG gene organization, expression, and chromosome map location on 8q
RL Genomics 51:468-471 (1998).
RN [2]; RE0017411.
RX PUBMED: 10479723.
RA Stegmann K., Boecker J., Kosan C., Ermert A., Kunz J., Koch M. C.
RT Human transcription factor SLUG: mutation analysis in patients with neural tube defects and identification of a missense mutation (D119E) in the Slug subfamily-defining region
RL Mutat. Res. 406:63-69 (1999).
RN [3]; RE0017418.
RX PUBMED: 9659933.
RA Jiang R., Lan Y., Norton C. R., Sundberg J. P., Gridley T.
RT The Slug gene is not essential for mesoderm or neural crest development in mice
RL Dev. Biol. 198:277-285 (1998).
RN [4]; RE0065166.
RX PUBMED: 19448627.
RA Wang S. P., Wang W. L., Chang Y. L., Wu C. T., Chao Y. C., Kao S. H., Yuan A., Lin C. W., Yang S. C., Chan W. K., Li K. C., Hong T. M., Yang P. C.
RT p53 controls cancer cell invasion by inducing the MDM2-mediated degradation of Slug.
RL Nat. Cell Biol. 11:694-704 (2009).
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