AC T11247
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ID T11247
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DT 16.11.2007 (created); djp.
DT 01.04.2010 (updated); jig.
CO Copyright (C), QIAGEN.
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FA Hesx1
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SY Hes1; Rathke's pouch homeobox protein; Rathke's pouch homeobox protein; Rpx.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G006198 Hesx1.
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CL C0018; paired-homeo.
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SZ 185 AA; 21.6 kDa (cDNA) (calc.).
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SQ MSPSLREGAQLRESKPAPCSFSIESILGLDQKKDCTTSVRPHRPWTDTCGNSEKDGNPPL
SQ HAPDLPSETSFPCPVDHPRPEERAPKYENYFSASETRSLKRELSWYRGRRPRTAFTQNQV
SQ EVLENVFRVNCYPGIDIREDLAQKLNLEEDRIQIWFQNRRAKMKRSRRESQFLMARKPFN
SQ PDLLK
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FT 21 28 
conserved octapeptide [3].
FT 106 166 
PS50071; HOMEOBOX_2.
FT 108 164 
PS50552; PAX.
FT 108 170 
SM00389; HOX_1.
FT 109 165 
PF00046; Homeobox domain.
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IN T27826 Dnmt1; mouse, Mus musculus.
IN T19534 ZNF592; mouse, Mus musculus.
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DR TRANSPATH: MO000117916.
DR EMBL: X80040;
DR UniProtKB: Q61658;
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RN [1]; RE0011563.
RX PUBMED: 7876132.
RA Thomas P. Q., Johnson B. V., Rathjen J., Rathjen P. D.
RT Sequence, genomic organization, and expression of the novel homeobox gene Hesx1
RL J. Biol. Chem. 270:3869-3875 (1995).
RN [2]; RE0013770.
RX PUBMED: 9620767.
RA Dattani M. T., Martinez-Barbera J.-P., Thomas P. Q., Brickman J. M., Gupta R., Martensson I.-L., Toresson H., Fox M., Wales J. K. H., Hindmarsh P. C., Krauss S., Beddington R. S. P., Robinson I. C. A. F.
RT Mutations in the homeobox gene HESX1/Hesx1 associated with septo-optic dysplasia in human and mouse
RL Nat. Genet. 19:125-133 (1998).
RN [3]; RE0014753.
RX PUBMED: 8565852.
RA Hermesz E., Mackem S., Mahon K. A.
RT Rpx: a novel anterior-restricted homeobox gene progressively activated in the prechordal plate, anterior neural plate and Rathke's pouch of the mouse embryo
RL Development 122:41-52 (1996).
RN [4]; RE0066383.
RX PUBMED: 17931718.
RA Sajedi E., Gaston-Massuet C., Andoniadou C. L., Signore M., Hurd P. J., Dattani M., Martinez-Barbera J. P.
RT DNMT1 interacts with the developmental transcriptional repressor HESX1.
RL Biochim. Biophys. Acta 1783:131-143 (2008).
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