AC T11343
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ID T11343
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DT 20.11.2007 (created); man.
DT 04.07.2016 (updated); sup.
CO Copyright (C), QIAGEN.
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FA TBX2
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SY T-box protein 2.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G002676 Tbx2.
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CL C0044; T-box.
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SZ 701 AA; 74.2 kDa (cDNA) (calc.).
XX
SQ MAYHPFHAPRPADFPMSAFLAAAQPSFFPALALPPGALGKPLPDPGLAGAAAAAAAAAAA
SQ AEAGLHVSALGPHPPAAHLRSLKSLEPEDEVEDDPKVTLEAKELWDQFHKLGTEMVITKS
SQ GRRMFPPFKVRVSGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADPEMPKRMYIHP
SQ DSPATGEQWMAKPVAFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTF
SQ RTYVFPETDFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREKRKQLTLPTLRLYEEH
SQ CKPERDGAESDASSCDPPPAREPPPSPSAAPSPLRLHRARAEEKPGAADSDPEPERTGEE
SQ RSAAPLCRSPSRDASPARLTEPERSRERRSPERCSKEPTEGGGDGPFSLRSLEKERPEAR
SQ RKDEGRKDVGEGKEPSLAPLVVQTDSASPLGAGHLPGLAFSSHLHGQQFFGPLGACQPLF
SQ LHPGQFAMGPGAFSAMGMGHLLASVAGGSGSSGGAGPGTAAGLDAGGLGPAASAASTAAP
SQ FPFHLSQHMLASQGIPMPTFGGLFPYPYTYMAAAAAAASALPATSAAAAAAAAAGSLSRS
SQ PFLGSARPRLRFSPYQIPVTIPPSTSLLTTGLAAEGSKGGNSREPSPLPELALRKVGGPS
SQ RGALSPSGSAKEAASELQRIQRLVSGLESQRALSPGRESPK
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SC translated from EMBL #U15566
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FT 94 282 SM00425; tbox5.
FT 96 278 PF00907; T-box.
FT 99 277 PS50252; TBOX_3.
FT 167 692 PF00478; IMP dehydrogenase / GMP reductase domain.
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IN T00722 pRb; human, Homo sapiens.
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MX M08900 V$TBX2RELATED_Q6.
MX M03889 V$TBX2_Q2.
MX M08831 V$TBX2_Q5.
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BS R09933.
BS R15796.
BS R30662.
BS R24615.
BS R11043.
BS R11044.
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DR TRANSPATH: MO000118143.
DR EMBL: U15566;
DR UniProtKB: Q60707;
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RN [1]; RE0015803.
RX PUBMED: 8798150.
RA Gibson-Brown J. J., Agulnik S. I., Chapman D. L., Alexiou M., Garvey N., Silver L. M., Papaioannou V. E.
RT Evidence of a role for T-box genes in the evolution of limb morphogenesis and the specification of forelimb/hindlimb identity
RL Mech. Dev. 56:93-101 (1996).
RN [2]; RE0016860.
RX PUBMED: 9710594.
RA Carreira S., Dexter T. J., Yavuzer U., Easty D. J., Goding C. R.
RT Brachyury-related transcription factor Tbx2 and repression of the melanocyte-specific TRP-1 promoter
RL Mol. Cell. Biol. 18:5099-5108 (1998).
RN [3]; RE0053128.
RX PUBMED: 18025091.
RA Abrahams A., Mowla S., Parker M. I., Goding C. R., Prince S.
RT UV-mediated regulation of the anti-senescence factor Tbx2.
RL J. Biol. Chem. 283:2223-2230 (2008).
RN [4]; RE0070917.
RX PUBMED: 20534814.
RA Vance K. W., Shaw H. M., Rodriguez M., Ott S., Goding C. R.
RT The retinoblastoma protein modulates Tbx2 functional specificity.
RL Mol. Biol. Cell 21:2770-2779 (2010).
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