AC T14231
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ID T14231
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DT 28.03.2008 (created); pum.
DT 13.05.2008 (updated); pum.
CO Copyright (C), QIAGEN.
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FA RP58-isoform1
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SY 58 KDA repressor protein; TAZ-1; transcriptional repressor RP58; translin-associated zinc finger protein-1; ZBTB18; Zinc finger and BTB domain-containing protein 18; zinc finger protein 238; Zinc finger protein C2H2-171.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G003023 ZBTB18; HGNC: ZBTB18.
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CL C0001; CH; 2.3.3.16.1.1.
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SZ 522 AA; 58.3 kDa (cDNA) (calc.).
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SQ MEFPDHSRHLLQCLSEQRHQGFLCDCTVLVGDAQFRAHRAVLASCSMYFHLFYKDQLDKR
SQ DIVHLNSDIVTAPAFALLLEFMYEGKLQFKDLPIEDVLAAASYLHMYDIVKVCKKKLKEK
SQ ATTEADSTKKEEDASSCSDKVESLSDGSSHIAGDLPSDEDEGEDEKLNILPSKRDLAAEP
SQ GNMWMRLPSDSAGIPQAGGEAEPHATAAGKTVASPCSSTESLSQRSVTSVRDSADVDCVL
SQ DLSVKSSLSGVENLNSSYFSSQDVLRSNLVQVKVEKEASCDESDVGTNDYDMEHSTVKES
SQ VSTNNRVQYEPAHLAPLREDSVLRELDREDKASDDEMMTPESERVQVEGGMESSLLPYVS
SQ NILSPAGQIFMCPLCNKVFPSPHILQIHLSTHFREQDGIRSKPAADVNVPTCSLCGKTFS
SQ CMYTLKRHERTHSGEKPYTCTQCGKSFQYSHNLSRHAVVHTREKPHACKWCERRFTQSGD
SQ LYRHIRKFHCELVNSLSVKSEALSLPTVRDWTLEDSSQELWK
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SC translated from EMBL #AJ001388
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FT 1 115 
POZ domain [1].
FT 14 121 
PF00651; BTB/POZ domain.
FT 24 91 
PS50097; BTB.
FT 24 121 
SM00225; BTB_4.
FT 55 404 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 114 120 
NLS (nuclear localization signal), putative [1].
FT 370 392 
PF00096; zf-C2H2.
FT 370 392 
SM00355; c2h2final6.
FT 370 397 
PS50157; ZINC_FINGER_C2H2_2.
FT 372 392 
zinc finger (C2H2) [1].
FT 410 432 PF00096; zf-C2H2.
FT 410 432 SM00355; c2h2final6.
FT 410 437 PS50157; ZINC_FINGER_C2H2_2.
FT 412 432 zinc finger (C2H2) [1].
FT 438 460 PF00096; zf-C2H2.
FT 438 460 SM00355; c2h2final6.
FT 438 465 PS50157; ZINC_FINGER_C2H2_2.
FT 440 460 zinc finger (C2H2) [1].
FT 466 489 PF00096; zf-C2H2.
FT 466 489 PS50157; ZINC_FINGER_C2H2_2.
FT 466 489 SM00355; c2h2final6.
FT 468 489 zinc finger (C2H2) [1].
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IN T27196 DNA (cytosine-5)-methyltransferase 3A-isoform1; mouse, Mus musculus.
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MX M00532 V$RP58_01.
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BS R12112.
BS R12113.
BS R12114.
BS R12115.
BS R12116.
BS R12117.
BS R12118.
BS R12119.
BS R12120.
BS R12121.
BS R12122.
BS R12123.
BS R12124.
BS R12125.
BS R12126.
BS R12127.
BS R12128.
BS R12129.
BS R12130.
BS R12131.
BS R12132.
BS R12133.
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DR TRANSPATH: MO000125521.
DR EMBL: AJ001388;
DR UniProtKB: Q99592-1;
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RN [1]; RE0017569.
RX PUBMED: 9756912.
RA Aoki K., Meng G., Suzuki K., Takashi T., Kameoka Y., Nakahara K., Ishida R., Kasai M.
RT RP58 associates with condensed chromatin and mediates a sequence-specific transcriptional repression.
RL J. Biol. Chem. 273:26698-26704 (1998).
RN [2]; RE0038072.
RX PUBMED: 11350943.
RA Fuks F., Burgers W. A., Godin N., Kasai M., Kouzarides T.
RT Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription
RL EMBO J. 20:2536-44 (2001).
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