AC T17043
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ID T17043
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DT 27.10.2009 (created); mkl.
DT 11.01.2016 (updated); mkl.
CO Copyright (C), QIAGEN.
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FA Sox-4
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SY EVI16; Sox-4; SOX4; SRY (sex determining region Y)-box 4.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G002877 SOX4; HGNC: SOX4.
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CL C0015; HMG.
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SZ 474 AA; 47.3 kDa (cDNA) (calc.).
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SQ MVQQTNNAENTEALLAGESSDSGAGLELGIASSPTPGSTASTGGKADDPSWCKTPSGHIK
SQ RPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPFIREAERLRLKHM
SQ ADYPDYKYRPRKKVKSGNANSSSSAAASSKPGEKGDKVGGSGGGGHGGGGGGGSSNAGGG
SQ GGGASGGGANSKPAQKKSCGSKVAGGAGGGVSKPHAKLILAGGGGGGKAAAAAAASFAAE
SQ QAGAAALLPLGAAADHHSLYKARTPSASASASSAASASAALAAPGKHLAEKKVKRVYLFG
SQ GLGTSSSPVGGVGAGADPSDPLGLYEEEGAGCSPDAPSLSGRSSAASSPAAGRSPADHRG
SQ YASLRAASPAPSSAPSHASSSASSHSSSSSSSGSSSSDDEFEDDLLDLNPSSNFESMSLG
SQ SFSSSSALDRDLDFNFEPGSGSHFEFPDYCTPEVSEMISGDWLESSISNLVFTY
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SC Swiss-Prot#Q06945
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FT 58 128 
SM00398; hmgende2.
FT 59 127 
PF00505; HMG (high mobility group) box.
FT 59 127 
PS50118; HMG_BOX_2.
FT 76 419 
PF00478; IMP dehydrogenase / GMP reductase domain.
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IN T15118 CBP; Mammalia.
IN T23091 p300; Mammalia.
IN T00671 p53; human, Homo sapiens.
IN T18226 plakoglobin; human, Homo sapiens.
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MX M01308 V$SOX4_01.
MX M07614 V$SOX4_Q3.
MX M03849 V$SOX4_Q5.
MX M07268 V$SOX4_Q5_02.
MX M02909 V$SOX5_07.
MX M08899 V$SOX_Q4.
MX M01014 V$SOX_Q6.
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BS R22451.
BS R63278.
BS R59549.
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DR TRANSPATH: MO000163175.
DR EMBL: X65661;
DR EMBL: X70683;
DR UniProtKB: Q06945;
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RN [1]; RE0004341.
RX PUBMED: 1614875.
RA Denny P., Swift S., Brand N., Dabhade N., Barton P., Ashworth A.
RT A conserved family of genes related to the testis determining gene, SRY
RL Nucleic Acids Res. 20:2887-2887 (1992).
RN [2]; RE0005012.
RX PUBMED: 8268656.
RA Farr C. J., Easty D. J., Ragoussis J., Collignon J., Lovell-Badge R., Goodfellow P. N.
RT Characterization and mapping of the human SOX4 gene
RL Mamm. Genome 4:577-584 (1993).
RN [3]; RE0017072.
RX PUBMED: 9730625.
RA Critcher R., Stitson R. N., Wade-Martins R., Easty D. J., Farr C. J.
RT Assignment of Sox4 to mouse chromosome 13 bands A3-A5 by fluorescence in situ hybridization; refinement2 of the human SOX4 location to 6p22.3 and of SOX20 to chromosome 17p12.3
RL Cytogenet. Cell Genet. 81:294-295 (1998).
RN [4]; RE0067005.
RX PUBMED: 16631117.
RA Pan X., Li H., Zhang P., Jin B., Man J., Tian L., Su G., Zhao J., Li W., Liu H., Gong W., Zhou T., Zhang X.
RT Ubc9 interacts with SOX4 and represses its transcriptional activity.
RL Biochem. Biophys. Res. Commun. 344:727-734 (2006).
RN [5]; RE0067035.
RX PUBMED: 19234109.
RA Pan X., Zhao J., Zhang W. N., Li H. Y., Mu R., Zhou T., Zhang H. Y., Gong W. L., Yu M., Man J. H., Zhang P. J., Li A. L., Zhang X. M.
RT Induction of SOX4 by DNA damage is critical for p53 stabilization and function.
RL Proc. Natl. Acad. Sci. USA 106:3788-3793 (2009).
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//