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TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN


AC T17302 XX ID T17302 XX DT 25.02.2002 (created); cch. DT 08.02.2012 (updated); grs. CO Copyright (C), QIAGEN. XX FA p53{p} XX OS human, Homo sapiens OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates XX EX human, Homo sapiens,fibroblast,,adult; detectable; Western blot; protein; [2]. XX IN T05038 ADA3; human, Homo sapiens. XX BS R30014. BS R32740. XX DR TRANSPATH: MO000023558. XX RN [1]; RE0020896. RX PUBMED: 10432310. RA Craig A. L., Burch L., Vojtesek B., Mikutowska J., Thompson A., Hupp T. R. RT Novel phosphorylation sites of human tumour suppressor protein p53 at Ser20 and Thr18 that disrupt the binding of mdm2 (mouse double minute 2) protein are modified in human cancers RL Biochem. J. 342:133-141 (1999). RN [2]; RE0021158. RX PUBMED: 10706102. RA Buschmann T., Adler V., Matusevich E., Fuchs S. Y., Ronai Z. RT p53 phosphorylation and association with murine double minute 2, c-Jun NH2-terminal kinase, p14ARF, and p300/CBP during the cell cycle and after exposure to ultraviolet irradiation RL Cancer Res. 60:896-900 (2000). RN [3]; RE0048945. RX PUBMED: 15668906. RA Weebadda W. K., Jackson T. J., Lin A. W. RT Expression of p16INK4A variants in senescent human fibroblasts independent of protein phosphorylation. RL J. Cell. Biochem. 94:1135-1147 (2005). RN [4]; RE0050898. RX PUBMED: 9371494. RA Mayo L. D., Turchi J. J., Berberich S. J. RT Mdm-2 phosphorylation by DNA-dependent protein kinase prevents interaction with p53. RL Cancer Res. 57:5013-5016 (1997). RN [5]; RE0053628. RX PUBMED: 7479067. RA Zhang W. W., Charest H., Matlashewski G. RT The expression of biologically active human p53 in Leishmania cells: a novel eukaryotic system to produce recombinant proteins. RL Nucleic Acids Res. 23:4073-4080 (1995). RN [6]; RE0064497. RX PUBMED: 18243116. RA Kitagawa M., Lee S. H., McCormick F. RT Skp2 suppresses p53-dependent apoptosis by inhibiting p300. RL Mol. Cell 29:217-231 (2008). RN [7]; RE0066926. RX PUBMED: 19049493. RA Cuesta A., Zambrano A., Royo M., Pascual A. RT The tumour suppressor p53 regulates the expression of amyloid precursor protein (APP). RL Biochem. J. 418:643-650 (2009). XX //