AC T22502
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ID T22502
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DT 30.11.2009 (created); grs.
DT 29.11.2011 (updated); yre.
CO Copyright (C), QIAGEN.
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FA IkappaBzeta-isoform1
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SY FLJ30225; FLJ34463; I-kappa-B-zeta; IkappaBzeta; IkB-zeta; IKBZ; IL-1 inducible nuclear ankyrin-repeat protein; INAP; Mail; MAIL-L; Molecule possessing ankyrin repeats induced by lipopolysaccharide; NF-kappa-B inhibitor zeta; NFKBIZ; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G034821 NFKBIZ; HGNC: NFKBIZ.
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CL C0020; Rel; 6.1.2.1.5.1.
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SZ 718 AA; 78.1 kDa (calc.).
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SQ MIVDKLLDDSRGGEGLRDAAGGCGLMTSPLNLSYFYGASPPAAAPGACDASCSVLGPSAP
SQ GSPGSDSSDFSSASSVSSCGAVESRSRGGARAERQPVEPHMGVGRQQRGPFQGVRVKNSV
SQ KELLLHIRSHKQKASGQAVDDFKTQGVNIEQFRELKNTVSYSGKRKGPDSLSDGPACKRP
SQ ALLHSQFLTPPQTPTPGESMEDVHLNEPKQESSADLLQNIINIKNECSPVSLNTVQVSWL
SQ NPVVVPQSSPAEQCQDFHGGQVFSPPQKCQPFQVRGSQQMIDQASLYQYSPQNQHVEQQP
SQ HYTHKPTLEYSPFPIPPQSPAYEPNLFDGPESQFCPNQSLVSLLGDQRESENIANPMQTS
SQ SSVQQQNDAHLHSFSMMPSSACEAMVGHEMASDSSNTSLPFSNMGNPMNTTQLGKSLFQW
SQ QVEQEESKLANISQDQFLSKDADGDTFLHIAVAQGRRALSYVLARKMNALHMLDIKEHNG
SQ QSAFQVAVAANQHLIVQDLVNIGAQVNTTDCWGRTPLHVCAEKGHSQVLQAIQKGAVGSN
SQ QFVDLEATNYDGLTPLHCAVIAHNAVVHELQRNQQPHSPEVQELLLKNKSLVDTIKCLIQ
SQ MGAAVEAKDRKSGRTALHLAAEEANLELIRLFLELPSCLSFVNAKAYNGNTALHVAASLQ
SQ YRLTQLDAVRLLMRKGADPSTRNLENEQPVHLVPDGPVGEQIRRILKGKSIQQRAPPY
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SC Swiss-Prot#Q9BYH8-1
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IN T09439 (NF-kappaB1)2; mouse, Mus musculus.
IN T17520 NF-kappaB1; Mammalia.
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DR TRANSPATH: MO000165400.
DR UniProtKB: Q9BYH8-1; BZ_HUMAN.
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RN [1]; RE0069938.
RX PUBMED: 19783680.
RA Seshadri S., Kannan Y., Mitra S., Parker-Barnes J., Wewers M. D.
RT MAIL regulates human monocyte IL-6 production.
RL J. Immunol. 183:5358-5368 (2009).
RN [2]; RE0071600.
RX PUBMED: 18436238.
RA Trinh D. V., Zhu N., Farhang G., Kim B. J., Huxford T.
RT The nuclear I kappaB protein I kappaB zeta specifically binds NF-kappaB p50 homodimers and forms a ternary complex on kappaB DNA.
RL J. Mol. Biol. 379:122-135 (2008).
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