AC T22801
XX
ID T22801
XX
DT 10.04.2002 (created); spi.
DT 15.09.2015 (updated); jmh.
CO Copyright (C), QIAGEN.
XX
FA Notch1
XX
SY HN1; neurogenic locus Notch homolog protein 1; NOTCH; TAN1; translocation-associated Notch protein TAN-1.
XX
OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
XX
GE G006478 NOTCH1; HGNC: NOTCH1.
XX
IN T06586 gfi1b; human, Homo sapiens.
XX
BS R37234.
BS R69718.
BS R69719.
BS R63989.
BS R65002.
XX
DR TRANSPATH: MO000030959.
DR UniProtKB: P46531;
XX
RN [1]; RE0035992.
RX PUBMED: 14592976.
RA Nie L., Xu M., Vladimirova A., Sun X. H.
RT Notch-induced E2A ubiquitination and degradation are controlled by MAP kinase activities.
RL EMBO J. 22:5780-5792 (2003).
RN [2]; RE0049559.
RX PUBMED: 15650752.
RA Cohen L. Y., Bourbonniere M., Sabbagh L., Bouchard A., Chew T., Jeannequin P., Lazure C., Sekaly R. P.
RT Notch1 antiapoptotic activity is abrogated by caspase cleavage in dying T lymphocytes.
RL Cell Death Differ. 12:243-254 (2005).
RN [3]; RE0066377.
RX PUBMED: 12107827.
RA Nickoloff B. J., Qin J. Z., Chaturvedi V., Denning M. F., Bonish B., Miele L.
RT Jagged-1 mediated activation of notch signaling induces complete maturation of human keratinocytes through NF-kappaB and PPARgamma.
RL Cell Death Differ. 9:842-855 (2002).
RN [4]; RE0066431.
RX PUBMED: 18604200.
RA Kolev V., Mandinova A., Guinea-Viniegra J., Hu B., Lefort K., Lambertini C., Neel V., Dummer R., Wagner E. F., Dotto G. P.
RT EGFR signalling as a negative regulator of Notch1 gene transcription and function in proliferating keratinocytes and cancer.
RL Nat. Cell Biol. 10:902-911 (2008).
RN [5]; RE0068123.
RX PUBMED: 20118921.
RA Ishitani T., Hirao T., Suzuki M., Isoda M., Ishitani S., Harigaya K., Kitagawa M., Matsumoto K., Itoh M.
RT Nemo-like kinase suppresses Notch signalling by interfering with formation of the Notch active transcriptional complex.
RL Nat. Cell Biol. 12:278-285 (2010).
XX
//