AC T23095
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ID T23095
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DT 12.02.2006 (created); sbr.
DT 10.04.2013 (updated); yre.
CO Copyright (C), QIAGEN.
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FA MTG8
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SY AML1T1; CBFA2T1; CDR; ETO; Hs.166094; Hs.31551; MGC2796; MTG8; MTG8b; ZMYND2.
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OS Mammalia
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia
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IN T16043 BCL-6; Mammalia.
IN T16056 RBPJK; Mammalia.
IN T08482 VDR-isoform1; human, Homo sapiens.
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DR TRANSPATH: MO000066105.
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RN [1]; RE0035187.
RX PUBMED: 10973986.
RA Wood J. D., Nucifora FC J. r., Duan K., Zhang C., Wang J., Kim Y., Schilling G., Sacchi N., Liu J. M., Ross C. A.
RT Atrophin-1, the dentato-rubral and pallido-luysian atrophy gene product, interacts with ETO/MTG8 in the nuclear matrix and represses transcription.
RL J. Cell Biol. 150:939-948 (2000).
RN [2]; RE0038073.
RX PUBMED: 11533236.
RA Amann J. M., Nip J., Strom D. K., Lutterbach B., Harada H., Lenny N., Downing J. R., Meyers S., Hiebert S. W.
RT ETO, a target of t(8;21) in acute leukemia, makes distinct contacts with multiple histone deacetylases and binds mSin3A through its oligomerization domain
RL Mol. Cell. Biol. 21:6470-83 (2001).
RN [3]; RE0040036.
RX PUBMED: 14551142.
RA Chevallier N., Corcoran C. M., Lennon C., Hyjek E., Chadburn A., Bardwell V. J., Licht J. D., Melnick A.
RT ETO protein of t(8;21) AML is a corepressor for Bcl-6 B-cell lymphoma oncoprotein
RL Blood 103:1454-63 (2004).
RN [4]; RE0045613.
RX PUBMED: 9447981.
RA Kitabayashi I., Ida K., Morohoshi F., Yokoyama A., Mitsuhashi N., Shimizu K., Nomura N., Hayashi Y., Ohki M.
RT The AML1-MTG8 leukemic fusion protein forms a complex with a novel member of the MTG8(ETO/CDR) family, MTGR1
RL Mol. Cell. Biol. 18:846-58 (1998).
RN [5]; RE0045614.
RX PUBMED: 10887131.
RA Shimada H., Ichikawa H., Nakamura S., Katsu R., Iwasa M., Kitabayashi I., Ohki M.
RT Analysis of genes under the downstream control of the t(8;21) fusion protein AML1-MTG8: overexpression of the TIS11b (ERF-1, cMG1) gene induces myeloid cell proliferation in response to G-CSF
RL Blood 96:655-63 (2000).
RN [6]; RE0047451.
RX PUBMED: 12460926.
RA Puccetti E., Obradovic D., Beissert T., Bianchini A., Washburn B., Chiaradonna F., Boehrer S., Hoelzer D., Ottmann O. G., Pelicci P. G., Nervi C., Ruthardt M.
RT AML-associated translocation products block vitamin D(3)-induced differentiation by sequestering the vitamin D(3) receptor.
RL Cancer Res. 62:7050-7058 (2002).
RN [7]; RE0048494.
RX PUBMED: 9819404.
RA Lutterbach B., Westendorf J. J., Linggi B., Patten A., Moniwa M., Davie J. R., Huynh K. D., Bardwell V. J., Lavinsky R. M., Rosenfeld M. G., Glass C., Seto E., Hiebert S. W.
RT ETO, a target of t(8;21) in acute leukemia, interacts with the N-CoR and mSin3 corepressors.
RL Mol. Cell. Biol. 18:7176-7184 (1998).
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