AC T27152
XX
ID T27152
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DT 15.04.2013 (created); mkl.
DT 24.07.2014 (updated); yre.
CO Copyright (C), QIAGEN.
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FA TLX-isoform1
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SY HTLL; NR2E1; tailless homolog; TLL; TLX.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G002807 NR2E1; HGNC: NR2E1.
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CL C0002; CC (rec).
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SZ 385 AA; 42.6 kDa (calc.).
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SQ MSKPAGSTSRILDIPCKVCGDRSSGKHYGVYACDGCSGFFKRSIRRNRTYVCKSGNQGGC
SQ PVDKTHRNQCRACRLKKCLEVNMNKDAVQHERGPRTSTIRKQVALYFRGHKEENGAAAHF
SQ PSAALPAPAFFTAVTQLEPHGLELAAVSTTPERQTLVSLAQPTPKYPHEVNGTPMYLYEV
SQ ATESVCESAARLLFMSIKWAKSVPAFSTLSLQDQLMLLEDAWRELFVLGIAQWAIPVDAN
SQ TLLAVSGMNGDNTDSQKLNKIISEIQALQEVVARFRQLRLDATEFACLKCIVTFKAVPTH
SQ SGSELRSFRNAAAIAALQDEAQLTLNSYIHTRYPTQPCRFGKLLLLLPALRSISPSTIEE
SQ VFFKKTIGNVPITRLLSDMYKSSDI
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SC translated from EMBL #AF220532
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FT 13 86 
SM00399; c4gold.
FT 13 90 
PS51030; NUCLEAR_REC_DBD_2.
FT 14 91 
PF00105; Zinc finger, C4 type (two domains).
FT 16 101 
DNA-binding domain [2].
FT 34 38 
P-box [2].
FT 53 59 
D-box [2].
FT 83 101 
T-box [2].
FT 95 101 
A-box [2].
FT 180 385 
ligand-binding domain [2].
FT 187 354 
SM00430; holi.
FT 190 379 PF00104; Ligand-binding domain of nuclear hormon.
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IN T21924 BCL-11A; human, Homo sapiens.
IN T22468 BCL11A-isoform1; human, Homo sapiens.
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DR TRANSPATH: MO000288785.
DR EMBL: AF220532;
DR UniProtKB: Q9Y466;
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RN [1]; RE0016939.
RX PUBMED: 11073974.
RA Kobayashi M., Yu R. T., Yasuda K., Umesono K.
RT Cell-type-specific regulation of the retinoic acid receptor mediated by the orphan nuclear receptor TLX
RL Mol. Cell. Biol. 20:8731-8739 (2000).
RN [2]; RE0016941.
RX PUBMED: 9628820.
RA Jackson A., Panayiotidis P., Foroni L.
RT The human homologue of the Drosophila tailless gene (TLX): characterization and mapping to a region of common deletion in human lymphoid leukemia on chromosome 6q21.
RL Genomics 50:34-43 (1998).
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