AC T34790
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ID T34790
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DT 12.02.2006 (created); sbr.
DT 11.08.2014 (updated); yre.
CO Copyright (C), QIAGEN.
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FA PCGF4
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SY B lymphoma Mo-MLV insertion region (mouse); BMI1; PCGF4; Polycomb complex protein BMI-1; Polycomb group RING finger protein 4; RING finger protein 51.
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OS Mammalia
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia
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IN T15303 E2F-6; Mammalia.
IN T18825 M33; human, Homo sapiens.
IN T34790 PCGF4; Mammalia.
IN T34675 RING1; human, Homo sapiens.
IN T16158 RING1B; human, Homo sapiens.
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BS R72983.
BS R72985.
BS R72978.
BS R72982.
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DR TRANSPATH: MO000062748.
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RN [1]; RE0013507.
RX PUBMED: 9009205.
RA Alkema M. J., Bronk M., Verhoeven E., Otte A., van't Veer L. J., Berns A., van Lohuizen M.
RT Identification of Bmi1-interacting proteins as constituents of a multimeric mammalian polycomb complex.
RL Genes Dev. 11:226-240 (1997).
RN [2]; RE0027627.
RX PUBMED: 11171983.
RA Trimarchi J. M., Fairchild B., Wen J., Lees J. A.
RT The E2F6 transcription factor is a component of the mammalian Bmi1-containing polycomb complex.
RL Proc. Natl. Acad. Sci. USA 98:1519-24 (2001).
RN [3]; RE0031450.
RX PUBMED: 15009096.
RA Obuse C., Yang H., Nozaki N., Goto S., Okazaki T., Yoda K.
RT Proteomics analysis of the centromere complex from HeLa interphase cells: UV-damaged DNA binding protein 1 (DDB-1) is a component of the CEN-complex, while BMI-1 is transiently co-localized with the centromeric region in interphase.
RL Genes Cells 9:105-20 (2004).
RN [4]; RE0036322.
RX PUBMED: 14965441.
RA Raaphorst F. M., Meijer C. J., Fieret E., Blokzijl T., Mommers E., Buerger H., Packeisen J., Sewalt R. A., Otte A. P., van Diest P. J.
RT Poorly differentiated breast carcinoma is associated with increased expression of the human polycomb group EZH2 gene
RL Neoplasia 5:481-8 (2003).
RN [5]; RE0036324.
RX PUBMED: 15105378.
RA Sun L. Q., Lee D. W., Zhang Q., Xiao W., Raabe E. H., Meeker A., Miao D., Huso D. L., Arceci R. J.
RT Growth retardation and premature aging phenotypes in mice with disruption of the SNF2-like gene, PASG
RL Genes Dev. 18:1035-46 (2004).
RN [6]; RE0036325.
RX PUBMED: 9121482.
RA Gunster M. J., Satijn D. P., Hamer K. M., den Blaauwen J. L., de Bruijn D., Alkema M. J., van Lohuizen M., van Driel R., Otte A. P.
RT Identification and characterization of interactions between the vertebrate polycomb-group protein BMI1 and human homologs of polyhomeotic
RL Mol. Cell. Biol. 17:2326-35 (1997).
RN [7]; RE0036326.
RX PUBMED: 14982841.
RA Dukers D. F., van Galen J. C., Giroth C., Jansen P., Sewalt R. G., Otte A. P., Kluin-Nelemans H. C., Meijer C. J., Raaphorst F. M.
RT Unique polycomb gene expression pattern in Hodgkin's lymphoma and Hodgkin's lymphoma-derived cell lines
RL Am. J. Pathol. 164:873-81 (2004).
RN [8]; RE0036328.
RX PUBMED: 9571155.
RA Hashimoto N., Brock H. W., Nomura M., Kyba M., Hodgson J., Fujita Y., Takihara Y., Shimada K., Higashinakagawa T.
RT RAE28, BMI1, and M33 are members of heterogeneous multimeric mammalian Polycomb group complexes
RL Biochem. Biophys. Res. Commun. 245:356-65 (1998).
RN [9]; RE0036329.
RX PUBMED: 9722603.
RA Saurin A. J., Shiels C., Williamson J., Satijn D. P., Otte A. P., Sheer D., Freemont P. S.
RT The human polycomb group complex associates with pericentromeric heterochromatin to form a novel nuclear domain
RL J. Cell Biol. 142:887-98 (1998).
RN [10]; RE0036330.
RX PUBMED: 9627119.
RA Hemenway C. S., Halligan B. W., Levy L. S.
RT The Bmi-1 oncoprotein interacts with dinG and MPh2: the role of RING finger domains
RL Oncogene 16:2541-7 (1998).
RN [11]; RE0037451.
RX PUBMED: 11158321.
RA Satijn D. P., Hamer K. M., den Blaauwen J. J, Otte A. P.
RT The Polycomb Group Protein EED Interacts with YY1, and Both Proteins Induce Neural Tissue in Xenopus Embryos
RL Mol. Cell. Biol. 21:1360-1369 (2001).
RN [12]; RE0039933.
RX PUBMED: 9858531.
RA Satijn D. P., Otte A. P.
RT RING1 interacts with multiple Polycomb-group proteins and displays tumorigenic activity
RL Mol. Cell. Biol. 19:57-68 (1999).
RN [13]; RE0046087.
RX PUBMED: 12589020.
RA Voncken J. W., Roelen B. A., Roefs M., de Vries S., Verhoeven E., Marino S., Deschamps J., van Lohuizen M.
RT Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibition
RL Proc. Natl. Acad. Sci. USA 100:2468-73 (2003).
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