AC T00186
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ID T00186
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DT 26.01.1993 (created); ewi.
DT 17.09.2014 (updated); yre.
CO Copyright (C), QIAGEN.
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FA YB-1B
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SY BP-8; CSDA2; CSDB; DbpB; MDR-NF1; MGC104858; MGC110976; MGC117250; NSEP-1; NSEP1; nuclease sensitive element binding protein 1; Y box binding protein 1; YB-1; YB1; YBX1.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G004962 YBX1; HGNC: YBX1.
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CL C0019; CSD.
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SZ 324 AA; 35.9 kDa (cDNA) (calc.).
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SQ MSSEAETQQPPAAPPAAPALSAADTKPGTTGSGAGSGGPGGLTSAAPAGGDKKVIATKVL
SQ GTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGA
SQ EAANVTGPGGVPVQGSKYAADRNHYRRYPRRRGPPRNYQQNYQNSESGEKNEGSESAPEG
SQ QAQQRRPYRRRRFPPYYMRRPYGRRPQYSNPPVQGEVMEGADNQGAGEQGRPVRQNMYRG
SQ YRPRFRRGPPRQRQPREDGNEEDKENQGDETQGQQPPQRRYRRNFNYRRRRPENPKPQDG
SQ KETKAADPPAENSSAPEAEQGGAE
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SC Swiss-Prot#P67809
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FT 58 128 
PF00313; 'Cold-shock' DNA-binding domain.
FT 60 128 
SM00357; CSP.
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SF identical to YB-1B B except Ala-120 (Glu in YB-1B B) and divergent C-terminal 11 AA;
SF component of the NF-GMb T00573 DNA-binding activity / complex [2];
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FF repressor [2];
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IN T10782 Smad6; Mammalia.
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MX M03805 V$YB1_Q3.
MX M03862 V$YB1_Q4.
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BS R13280.
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DR TRANSPATH: MO000024757.
DR EMBL: M24070;
DR UniProtKB: P67809;
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RN [1]; RE0000590.
RX PUBMED: 2977358.
RA Sakura H., Maekawa T., Imamoto F., Yusuda K., Ishii S.
RT Two human genes isolated by a novel method encode DNA-binding proteins containing a common region of homology
RL Gene 73:499-507 (1988).
RN [2]; RE0006932.
RX PUBMED: 8710501.
RA Coles L. S., Diamond P., Occhiodoro F., Vadas M. A., Shannon M. F.
RT Cold shock domain proteins represses transcription from the GM-CSF promoter
RL Nucleic Acids Res. 24:2311-2317 (1996).
RN [3]; RE0047870.
RX PUBMED: 15840729.
RA Shen X., Valencia C. A., Szostak J. W., Dong B., Liu R.
RT Scanning the human proteome for calmodulin-binding proteins.
RL Proc. Natl. Acad. Sci. USA 102:5969-5974 (2005).
RN [4]; RE0052485.
RX PUBMED: 12674497.
RA Moraes K. C., Quaresma A. J., Maehnss K., Kobarg J.
RT Identification and characterization of proteins that selectively interact with isoforms of the mRNA binding protein AUF1 (hnRNP D).
RL Biol. Chem. 384:25-37 (2003).
RN [5]; RE0060449.
RX PUBMED: 16278212.
RA Dooley S., Said H. M., Gressner A. M., Floege J., En-Nia A., Mertens P. R.
RT Y-box protein-1 is the crucial mediator of antifibrotic interferon-gamma effects.
RL J. Biol. Chem. 281:1784-1795 (2006).
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