AC T10782
XX
ID T10782
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DT 10.03.2005 (created); nvo.
DT 26.05.2014 (updated); yre.
CO Copyright (C), QIAGEN.
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FA Smad6
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SY Smad-6.
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OS Mammalia
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia
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IN T14205 ALY; human, Homo sapiens.
IN T10835 arnt; human, Homo sapiens.
IN T28793 BCLAF1-isoform1; human, Homo sapiens.
IN T02498 CSDA-isoform1; human, Homo sapiens.
IN T10186 CtBP1-isoform1; mouse, Mus musculus.
IN T34296 DNA-directed RNA polymerases I, II, and III 17.1 kDa polypeptide; human, Homo sapiens.
IN T14721 DSIF-p14; human, Homo sapiens.
IN T08100 EWS; human, Homo sapiens.
IN T25799 hnRNPA1-B; human, Homo sapiens.
IN T25711 hnRPAB-isoform2; human, Homo sapiens.
IN T08835 Ku70-isoform1; human, Homo sapiens.
IN T34293 LSD1-isoform2; human, Homo sapiens.
IN T16985 nucleolin; human, Homo sapiens.
IN T10783 Smad1; Mammalia.
IN T09365 Smad6-A; human, Homo sapiens.
IN T25717 TFII-I-isoform1; human, Homo sapiens.
IN T34681 TRAP150; human, Homo sapiens.
IN T27177 Tsc-22-isoform2; human, Homo sapiens.
IN T00910 YB-1; human, Homo sapiens.
IN T00186 YB-1B; human, Homo sapiens.
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MX M08897 V$SMAD_Q4.
MX M00974 V$SMAD_Q6_01.
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BS R22200.
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DR TRANSPATH: MO000047652.
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RN [1]; RE0021582.
RX PUBMED: 10748100.
RA Kimura N., Matsuo R., Shibuya H., Nakashima K., Taga T.
RT BMP2-induced apoptosis is mediated by activation of the TAK1-p38 kinase pathway that is negatively regulated by Smad6
RL J. Biol. Chem. 275:17647-17652 (2000).
RN [2]; RE0027996.
RX PUBMED: 11278410.
RA Sasaki A., Masuda Y., Ohta Y., Ikeda K., Watanabe K.
RT Filamin associates with Smads and regulates transforming growth factor-beta signaling.
RL J. Biol. Chem. 276:17871-7 (2001).
RN [3]; RE0029297.
RX PUBMED: 11737269.
RA Yanagisawa M., Nakashima K., Takeda K., Ochiai W., Takizawa T., Ueno M., Takizawa M., Shibuya H., Taga T.
RT Inhibition of BMP2-induced, TAK1 kinase-mediated neurite outgrowth by Smad6 and Smad7.
RL Genes Cells 6:1091-9 (2001).
RN [4]; RE0030743.
RX PUBMED: 11376113.
RA Clarke T. R., Hoshiya Y., Yi S. E., Liu X., Lyons K. M., Donahoe P. K.
RT Mullerian inhibiting substance signaling uses a bone morphogenetic protein (BMP)-like pathway mediated by ALK2 and induces SMAD6 expression.
RL Mol. Endocrinol. 15:946-59 (2001).
RN [5]; RE0031933.
RX PUBMED: 14645520.
RA Lin X., Liang Y. Y., Sun B., Liang M., Shi Y., Brunicardi F. C., Shi Y., Feng X. H.
RT Smad6 recruits transcription corepressor CtBP to repress bone morphogenetic protein-induced transcription.
RL Mol. Cell. Biol. 23:9081-93 (2003).
RN [6]; RE0039135.
RX PUBMED: 14657019.
RA Koinuma D., Shinozaki M., Komuro A., Goto K., Saitoh M., Hanyu A., Ebina M., Nukiwa T., Miyazawa K., Imamura T., Miyazono K.
RT Arkadia amplifies TGF-beta superfamily signalling through degradation of Smad7
RL EMBO J. 22:6458-70 (2003).
RN [7]; RE0041180.
RX PUBMED: 12815042.
RA Imoto S., Sugiyama K., Muromoto R., Sato N., Yamamoto T., Matsuda T.
RT Regulation of transforming growth factor-beta signaling by protein inhibitor of activated STAT, PIASy through Smad3
RL J. Biol. Chem. 278:34253-8 (2003).
RN [8]; RE0046082.
RX PUBMED: 11483516.
RA Itoh F., Asao H., Sugamura K., Heldin C. H., ten Dijke P., Itoh S.
RT Promoting bone morphogenetic protein signaling through negative regulation of inhibitory Smads
RL EMBO J. 20:4132-42 (2001).
RN [9]; RE0046995.
RX PUBMED: 15221015.
RA Komuro A., Imamura T., Saitoh M., Yoshida Y., Yamori T., Miyazono K., Miyazawa K.
RT Negative regulation of transforming growth factor-beta (TGF-beta) signaling by WW domain-containing protein 1 (WWP1)
RL Oncogene 23:6914-23 (2004).
RN [10]; RE0049823.
RX PUBMED: 16951688.
RA Choi K. C., Lee Y. S., Lim S., Choi H. K., Lee C. H., Lee E. K., Hong S., Kim I. H., Kim S. J., Park S. H.
RT Smad6 negatively regulates interleukin 1-receptor-Toll-like receptor signaling through direct interaction with the adaptor Pellino-1.
RL Nat. Immunol. 7:1057-1065 (2006).
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