AC T16985
XX
ID T16985
XX
DT 18.01.2006 (created); res.
DT 26.06.2013 (updated); sup.
CO Copyright (C), QIAGEN.
XX
FA nucleolin
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SY protein C23.
XX
OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G006456 NCL; HGNC: NCL.
XX
SZ 710 AA; 76.6 kDa (cDNA) (calc.), 100 kDa (SDS) [2]
XX
SQ MVKLAKAGKNQGDPKKMAPPPKEVEEDSEDEEMSEDEEDDSSGEEVVIPQKKGKKAAATS
SQ AKKVVVSPTKKVAVATPAKKAAVTPGKKAAATPAKKTVTPAKAVTTPGKKGATPGKALVA
SQ TPGKKGAAIPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAA
SQ APASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEE
SQ DDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEG
SQ TEPTTAFNLFVGNLNFNKSAPELKTGISDVFAKNDLAVVDVRIGMTRKFGYVDFESAEDL
SQ EKALELTGLKVFGNEIKLEKPKGKDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAEIR
SQ LVSKDGKSKGIAYIEFKTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNST
SQ WSGESKTLVLSNLSYSATEETLQEVFEKATFIKVPQNQNGKSKGYAFIEFASFEDAKEAL
SQ NSCNKREIEGRAIRLELQGPRGSPNARSQPSKTLFVKGLSEDTTEETLKESFDGSVRARI
SQ VTDRETGSSKGFGFVDFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKGEGGFGGRGGGR
SQ GGFGGRGGGRGGRGGFGGRGRGGFGGRGGFRGGRGGGGDHKPQGKKTKFE
XX
SC Swiss-Prot#P19338
XX
FT 44 524 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 306 382 
PS50102; RRM.
FT 307 378 
SM00360; rrm1_1.
FT 308 377 
PF00076; RNA recognition motif. (a.k.a. RRM, RBD, or.
FT 392 465 
PS50102; RRM.
FT 393 461 
SM00360; rrm1_1.
FT 394 460 
PF00076; RNA recognition motif. (a.k.a. RRM, RBD, or.
FT 485 559 
PS50102; RRM.
FT 486 555 
SM00360; rrm1_1.
FT 487 554 
PF00076; RNA recognition motif. (a.k.a. RRM, RBD, or.
FT 571 643 PS50102; RRM.
FT 572 639 SM00360; rrm1_1.
FT 573 638 PF00076; RNA recognition motif. (a.k.a. RRM, RBD, or.
XX
IN T10782 Smad6; Mammalia.
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BS R56756.
BS R56765.
BS R29450.
XX
DR TRANSPATH: MO000057303.
DR SMARTDB: SB000119.
DR EMBL: M60858;
DR UniProtKB: P19338;
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RN [1]; RE0035741.
RX PUBMED: 10607589.
RA Dumler I., Stepanova V., Jerke U., Mayboroda O. A., Vogel F., Bouvet P., Tkachuk V., Haller H., Gulba D. C.
RT Urokinase-induced mitogenesis is mediated by casein kinase 2 and nucleolin.
RL Curr. Biol. 9:1468-1476 (1999).
RN [2]; RE0007007.
RX PUBMED: 7799955.
RA Dickinson L. A., Kohwi-Shigematsu T.
RT Nucleolin is a matrix attachment region DNA-binding protein that specifically recognizes a region with high base-unpairing potential
RL Mol. Cell. Biol. 15:456-465 (1995).
XX
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