AC T09365
XX
ID T09365
XX
DT 05.10.2006 (created); ask.
DT 25.01.2007 (updated); kau.
CO Copyright (C), QIAGEN.
XX
FA Smad6-A
XX
SY JV-15-1; Smad-6.
XX
OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
XX
GE G002407 SMAD6; HGNC: SMAD6.
XX
CL C0041; SMAD; 7.1.1.3.1.1.
XX
SZ 496 AA; 53.5 kDa (cDNA) (calc.).
XX
SQ MFRSKRSGLVRRLWRSRVVPNREEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEV
SQ RPVAPRRPRDAVGQRGAQGAGRRRRAGGPPRPMSEPGAGAGSSLLDVAEPGGPGWLPESD
SQ CETVTCCLFSERDAAGAPRDASDPLAGAALEPAGGGRSREARSRLLLLEQELKTVTYSLL
SQ KRLKERSLDTLLEAVESRGGVPGGCVLVPRADLRLGGQPAPPQLLLGRLFRWPDLQHAVE
SQ LKPLCGCHSFAAAADGPTVCCNPYHFSRLCGPESPPPPYSRLSPRDEYKPLDLSDSTLSY
SQ TETEATNSLITAPGEFSDASMSPDATKPSHWCSVAYWEHRTRVGRLYAVYDQAVSIFYDL
SQ PQGSGFCLGQLNLEQRSESVRRTRSKIGFGILLSKEPDGVWAYNRGEHPIFVNSPTLDAP
SQ GGRALVVRKVPPGYSIKVFDFERSGLQHAPEPDAADGPYDPNSVRISFAKGWGPCYSRQF
SQ ITSCPCWLEILLNNPR
XX
SC translated from EMBL #AF035528
XX
FT 1 223 
N-terminal domain [1].
FT 148 275 
PS51075; MH1.
FT 167 273 
SM00523; dwAneu5.
FT 169 270 
PF03165; MH1 domain.
FT 224 328 
Linker region [1].
FT 325 495 
PF03166; MH2 domain.
FT 329 496 
C-terminal domain [1].
FT 329 493 
SM00524; DWB.
FT 331 496 
PS51076; MH2.
XX
IN T10784 CtBP1; Mammalia.
IN T10782 Smad6; Mammalia.
XX
DR TRANSPATH: MO000088252.
DR EMBL: AF035528; AF035528.
DR EMBL: AF037469; AF037469.
DR UniProtKB: O43541-1;
XX
RN [1]; RE0015609.
RX PUBMED: 9436979.
RA Hata A., Lagna G., Massague J., Hemmati-Brivanlou A.
RT Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor
RL Genes Dev. 12:186-197 (1998).
RN [2]; RE0015642.
RX PUBMED: 9335505.
RA Imamura T., Takase M., Nishihara A., Oeda E., Hanai J., Kawabata M., Miyazono K.
RT Smad6 inhibits signalling by the TGF-beta superfamily
RL Nature 389:622-626 (1997).
XX
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