AC T00198
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ID T00198
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DT 14.12.1992 (created); ewi.
DT 22.11.2010 (updated); din.
CO Copyright (C), QIAGEN.
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FA DRTF1
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SY differentiation regulated factor 1.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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SF p50 and p30 are DNA-contacting polypeptides of DRTF complexes 1b and 1c;
SF DRTF complex 1a is phosphorylation-dependent;
SF like E2F, DRTF1 binding activity appears to be composed of a E2F- and a DP-component (E2F-1, -2, -3, -4 and DP-1, resp.) [5];
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FF down-regulated during differentiation;
FF functionally related to, but different from E2F (human);
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IN T01423 pRb; mouse, Mus musculus.
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BS R00326.
BS R02687.
BS R03467.
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DR TRANSPATH: MO000024765.
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RN [1]; RE0001675.
RX PUBMED: 1833634.
RA Murray E. J., Stott D., Rigby P. W. J.
RT Sequences and factors required for the F9 embryonal carcinoma stem cell E1a-like activity
RL Mol. Cell. Biol. 11:5534-5540 (1991).
RN [2]; RE0001744.
RX PUBMED: 1825349.
RA Shivji M. K. K., La Thangue N. B.
RT Multicomponent differentiation-regulated transcription factors in F9 embryonal carcinoma stem cells
RL Mol. Cell. Biol. 11:1686-1695 (1991).
RN [3]; RE0002069.
RX PUBMED: 2140887.
RA La Thangue N. B., Thimmappaya B., Rigby P. W. J.
RT The embryonal carcinoma stem cell E1a-like activity involves a differentiation-regulated transcription factor
RL Nucleic Acids Res. 18:2929-2938 (1990).
RN [4]; RE0002872.
RX PUBMED: 1834460.
RA Partridge J. F., La Thangue N. B.
RT A developmentally regulated and tissue-dependent transcription factor complexes with the retinoblastoma gene product
RL EMBO J. 10:3819-3827 (1991).
RN [5]; RE0003322.
RX PUBMED: 8446173.
RA Girling R., Partridge J. F., Bandara L. R., Burden N., Totty N. F., Hsuan J. J., La Thangue N. B.
RT A new component of the transcription factor DRTF1/E2F
RL Nature 362:83-87 (1993).
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