AC T00307
AS T00567.
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ID T00307
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DT 26.01.1993 (created); hse.
DT 17.04.2007 (updated); sra.
CO Copyright (C), QIAGEN.
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FA GATA-2
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SY GF-1; NF-E1b.
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OS chick, Gallus gallus
OC eukaryota; animalia; metazoa; chordata; vertebrata; aves; neornithes; neognathae; galliformes; phasianidae
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GE G043303 GATA2.
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CL C0004; CC; 2.2.1.1.2.
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SF pI 9.9;
SF expression reduces during erythrocyte differentiation [5];
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CP early erythroid cells; embryonic brain, liver, cardiac muscle, fibroblasts; adult kidney [2].
CN erythrocytes [5]; T-lymphocytes (MSB-1), embryonic skeletal muscle, adult liver [2] [5] [2].
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FF GATA-2 promotes proliferation of erythroid progenitor cells and inhibits their terminal differentiation [3];
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IN T00267 GATA-1; chick, Gallus gallus.
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MX M00076 V$GATA2_01.
MX M00348 V$GATA2_02.
MX M00349 V$GATA2_03.
MX M00203 V$GATA_C.
MX M00789 V$GATA_Q6.
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DR TRANSPATH: MO000024845.
DR UniProtKB: P23824;
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RN [1]; RE0000167.
RX PUBMED: 2225071.
RA Orkin S. H.
RT Globin gene regulation and switching: Circa 1990
RL Cell 63:665-672 (1990).
RN [2]; RE0000674.
RX PUBMED: 2249770.
RA Yamamoto M., Ko L. J., Leonard M. W., Beug H., Orkin S. H., Engel J. D.
RT Activity and tissue-specific expression of the transcription factor NF-E1 multigene family
RL Genes Dev. 4:1650-1662 (1990).
RN [3]; RE0009396.
RX PUBMED: 8504932.
RA Briegel K., Lim K.-C., Plank C., Beug H., Engel J. D., Zenke M.
RT Ectopic expression of a conditional GATA-2/estrogen receptor chimera arrests erythroid differentiation in a hormone-dependent manner
RL Genes Dev. 7:1097-1109 (1993).
RN [4]; RE0013392.
RX PUBMED: 8321208.
RA Ko L. J., Engel J. D.
RT DNA-binding specificities of the GATA transcription factor family.
RL Mol. Cell. Biol. 13:4011-4022 (1993).
RN [5]; RE0013440.
RX PUBMED: 8336726.
RA Rousseau S., Asselin M., Renaud J., Ruiz-Carrillo A.
RT Transcription of the histone H5 gene is regulated by three differentiation-specific enhancers.
RL Mol. Cell. Biol. 13:4904-4917 (1993).
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