AC T00613
AS T00083, T00092, T00153, T01202.
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ID T00613
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DT 15.10.1992 (created); ewi.
DT 16.12.2011 (updated); pch.
CO Copyright (C), QIAGEN.
XX
FA NF-Y
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SY alpha-CP1; CBF(2); CCAAT-binding factor; CP1; CP1 (human, rat); CP1, CBF(2); NF-Y; NF-YA + NF-YB; NF-YA(m):NF-YB(m):NF-YC(m); NF-YA:NF-YB:NF-YC; NFY; Nuclear Factor Y.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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HO AIC1.
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SF consists of 3 subunits: NF-YA T00615, NF-YB T00616, and NF-YC T02477 encoded by different genes;
SF previously was thought to be composed of seven polypeptides of three groups observed: alpha (35 kDa), beta (28, 27 kDa), gamma (33, 34, 37, 38 kDa);
SF stable alpha:beta association, weak association of gamma [8];
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FF activator;
FF required for reinitiation;
FF c-Myc binds the HAP domain of NF-Y and remains in a DNA-binding NF-Y complex [29];
XX
MX M00687 V$ALPHACP1_01.
MX M00287 V$NFY_01.
MX M00209 V$NFY_C.
MX M07302 V$NFY_Q3.
MX M00185 V$NFY_Q6.
MX M00775 V$NFY_Q6_01.
XX
BS R02874.
BS R02875.
BS R02876.
BS R02877.
BS R02878.
BS R02879.
BS R02880.
BS R02881.
BS R00022.
BS R21047.
BS R14553.
BS R00564.
BS R01858.
BS R02048.
BS R02888.
BS R00572.
BS R00766.
BS R14867.
BS R00232.
BS R00090.
BS R00228.
BS R16511.
BS R34164.
BS R34166.
BS R00511.
BS R16982.
BS R16986.
BS R28961.
BS R01076.
BS R01080.
BS R01081.
BS R01942.
BS R17113.
BS R27132.
BS R27133.
BS R27134.
BS R27136.
BS R27137.
BS R17073.
BS R27106.
BS R27112.
BS R27123.
BS R27125.
BS R27127.
BS R27158.
BS R27160.
BS R27167.
BS R27168.
BS R17127.
BS R03043.
BS R37549.
BS R03016.
BS R16544.
XX
DR TRANSPATH: MO000025054.
DR TRANSCOMPEL: C00004.
XX
RN [1]; RE0000036.
RX PUBMED: 3349524.
RA Chodosh L. A., Baldwin jr A. S., Carthew R. W., Sharp P. A.
RT Human CCAAT-Binding Proteins Have Heterologous Subunits
RL Cell 53:11-24 (1988).
RN [2]; RE0000110.
RX PUBMED: 3476205.
RA Dorn A., Bollekens J., Staub A., Benoist C., Mathis D.
RT A Multiplicity of CCAAT Box-Binding Proteins
RL Cell 50:863-872 (1987).
RN [3]; RE0000346.
RX PUBMED: 3181130.
RA Superti-Furga G., Barberis A., Schaffner G., Busslinger M.
RT The -117 mutation in Greek HPFH affects the binding of three nuclear factors to the CCAAT region of the gamma-globin gene
RL EMBO J. 7:3099-3107 (1988).
RN [4]; RE0000447.
RX PUBMED: 1698608.
RA Hooft van Huijsduijnen R., Li X. Y., Black D., Matthes H., Benoist C., Mathis D.
RT Co-evolution from yeast to mouse: cDNA cloning of the two NF-Y (CP-1/CBF) subunits
RL EMBO J. 9:3119-3127 (1990).
RN [5]; RE0000824.
RX PUBMED: 3038906.
RA Oikarinen J., Hatamochi A., de Crombrugghe B.
RT Separate Binding Sites for Nuclear Factor 1 and a CCAAT DNA Binding Factor in the Mouse alpha2(I) Collagen Promoter
RL J. Biol. Chem. 262:11064-11070 (1987).
RN [6]; RE0000825.
RX PUBMED: 3417682.
RA Karsenty G., Golumbek P., de Crombrugghe B.
RT Point Mutations and Small Substitution Mutations in Three Different Upstream Elements Inhibit the Activity of the Mouse alpha2(I) Collagen Promoter
RL J. Biol. Chem. 263:13909-13915 (1988).
RN [7]; RE0000889.
RX PUBMED: 3281949.
RA Hatamochi A., Golumbek P. T., an Schaftingen E., de Crombugghe B.
RT A CCAAT DNA Binding Factor Consisting of Two Different Components That Are Both Required for DNA Binding
RL J. Biol. Chem. 263:5940-5947 (1988).
RN [8]; RE0000946.
RX PUBMED: 2376599.
RA Kim C. G., Sheffery M.
RT Physical characterization of the purified CCAAT transcription factor, alpha-CP1
RL J. Biol. Chem. 265:13362-13369 (1990).
RN [9]; RE0000971.
RX PUBMED: 1900840.
RA Papazafiri P., Ogami K., Ramji D. P., Nicosia A., Monaci P., Cladaras C., Zannis V. I.
RT Promoter elements and factors involved in hepatic transcription of the human ApoA-I gene positive and negative regulators bind to overlapping sites
RL J. Biol. Chem. 266:5790-5797 (1991).
RN [10]; RE0001257.
RX PUBMED: 2905426.
RA Barnhart K. M., Kim C. G., Banerji S. S., Sheffery M.
RT Identification and Characterization of Multiple Erythroid Cell Proteins That Interact with the Promoter of the Murine alpha-Globin Gene
RL Mol. Cell. Biol. 8:3215-3226 (1988).
RN [11]; RE0001258.
RX PUBMED: 3185549.
RA Kim C. G., Barnhart K. M., Sheffery M.
RT Purification of Multiple Erythroid Cell Proteins That Bind the Promoter of the alpha-Globin Gene
RL Mol. Cell. Biol. 8:4270-4281 (1988).
RN [12]; RE0001259.
RX PUBMED: 3464831.
RA Cohen R. B., Sheffery M., Kim C. G.
RT Partial purification of a nuclear protein that binds to the CCAAT box of the mouse alpha1-globin gene
RL Mol. Cell. Biol. 6:821-832 (1986).
RN [13]; RE0001311.
RX PUBMED: 3141781.
RA Dorn A., Fehling H. J., Koch W., Le Meur M., Gerlinger P., Benoist C., Mathis D.
RT B-Cell Control Region at the 5' End of a Major Histocompatibility Complex Class II Gene: Sequences and Factors
RL Mol. Cell. Biol. 8:3975-3987 (1988).
RN [14]; RE0001435.
RX PUBMED: 2294402.
RA Taylor I. C. A., Kingston R. E.
RT Factor Substitution in a Human HSP70 Gene Promoter: TATA-Dependent and TATA-Independent Interactions
RL Mol. Cell. Biol. 10:165-175 (1990).
RN [15]; RE0001611.
RX PUBMED: 1672442.
RA Spanopoulou E., Giguere V., Grosveld F.
RT The functional domains of the murine Thy-1 gene promoter
RL Mol. Cell. Biol. 11:2216-2228 (1991).
RN [16]; RE0002047.
RX PUBMED: 2476717.
RA Mantovani R., Superti-Furga G., Gilman J., Ottolenghi S.
RT The deletion of the distal CCAAT box region of the Agamma-globin gene in black HPFH abolishes the binding of the erythroid specific protein NFE3 and of the CCAAT displacement protein
RL Nucleic Acids Res. 17:6681-6691 (1989).
RN [17]; RE0002066.
RX PUBMED: 2557588.
RA Ben-Hattar J., Beard P., Jiricny J.
RT Cytosine methylation in CTF and Sp1 recognition sites of an HSV tk promoter: effects on transcription in vivo and on factor binding in vitro
RL Nucleic Acids Res. 17:10179-10190 (1989).
RN [18]; RE0002078.
RX PUBMED: 1698280.
RA Fucharoen S., Shimizu K., Fukumaki Y.
RT A novel C-T transition within the distal CCAAT motif of the Ggamma-globin gene in the Japanese HPFH: implication of factor binding in elevated fetal globin expression
RL Nucleic Acids Res. 18:5245 (1990).
RN [19]; RE0002330.
RX PUBMED: 3114745.
RA Dorn A., Durand B., Marfing C., Le Meur M., Benoist C., Mathis D.
RT Conserved major histocompatibility complex class II boxes-X and Y-are transcriptional control elements and specifically bind nuclear proteins
RL Proc. Natl. Acad. Sci. USA 84:6249-6253 (1987).
RN [20]; RE0002593.
RX PUBMED: 3399893.
RA Maity S. N., Golumbek P. T., Karsenty G., de Crombrugghe B.
RT Selective Activation of Transcription by a Novel CCAAT Binding Factor
RL Science 241:582-584 (1988).
RN [21]; RE0002858.
RX PUBMED: 1644837.
RA Maity S. N., Sinha S., Ruteshouser E. C., de Crombrugghe B.
RT Three different polypeptides are necessary for DNA binding of the mammalian heteromeric CCAAT binding factor
RL J. Biol. Chem. 267:16574-16580 (1992).
RN [22]; RE0003160.
RX PUBMED: 1380453.
RA Mantovani R., Pessara U., Tronche F., Li X.-Y., Knapp A.-M., Pasquali J.-L., Benoist C., Mathis D.
RT Monoclonal antibodies to NF-Y define its function in MHC class II and albumin gene transcription
RL EMBO J. 11:3315-3322 (1992).
RN [23]; RE0003846.
RX PUBMED: 7814413.
RA Coustry P., Maity S. N., de Crombrugghe B.
RT Studies on transcriptional activation by the multimeric CCAAT-binding factor CBF
RL J. Biol. Chem. 270:468-475 (1995).
RN [24]; RE0008202.
RX PUBMED: 8444876.
RA Framson P., Bornstein P.
RT A serum response element and a binding site for NF-Y mediate the serum response of the human thrombospondin 1 gene
RL J. Biol. Chem. 268:4989-4996 (1993).
RN [25]; RE0009989.
RX PUBMED: 8348960.
RA Hatamochi A., de Crombrugghe B., Krieg T.
RT Purification of a novel factor which binds to the mouse alpha2 (I) collagen promoter
RL FEBS Lett. 327:325-331 (1993).
RN [26]; RE0022625.
RX PUBMED: 7509302.
RA Sohn K. Y., Maity S. N., de Crombrugghe B.
RT Studies on the structure of the mouse CBF-A gene and properties of a truncated CBF-A isoform generated from an alternatively spliced RNA.
RL Gene 139:147-153 (1994).
RN [27]; RE0022626.
RX PUBMED: 9712144.
RA Collins M., Smith A. A., Parker M. I.
RT Characterization of two distinct families of transcription factors that bind to the CCAAT box region of the human COL1A2 gene.
RL J. Cell. Biochem. 70:455-467 (1998).
RN [28]; RE0023840.
RX PUBMED: 11306579.
RA Imbriano C., Bolognese F., Gurtner A., Piaggio G., Mantovani R.
RT HSP-CBF is an NF-Y-dependent coactivator of the heat shock promoters CCAAT boxes.
RL J. Biol. Chem. 276:26332-26339 (2001).
RN [29]; RE0032153.
RX PUBMED: 11282029.
RA Izumi H., Molander C., Penn L. Z., Ishisaki A., Kohno K., Funa K.
RT Mechanism for the transcriptional repression by c-Myc on PDGF beta-receptor.
RL J. Cell Sci. 114:1533-44 (2001).
XX
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