AC T00615
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ID T00615
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DT 26.01.1993 (created); ewi.
DT 20.08.2012 (updated); mkl.
CO Copyright (C), QIAGEN.
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FA NF-YA-isoform1
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SY CBF-B (rat); CP1B (human, rat); HAP2 (yeast); NF-YA.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G004107 Nfya.
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CL C0075; heteromer-CCAAT; 4.2.1.0.1.1.
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SZ 346 AA; 36.8 kDa (calc.), 36.8 kDa (cDNA, 346 AA form), 34 kDa (cDNA, 318 AA form), 40 kDa (SDS)
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SQ MEQYTTNSNSSTEQIVVQAGQIQQQQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQPLM
SQ VQVSGGQLITSTGQPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQ
SQ VQGQQGQTQQIIIQQPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTILQ
SQ QVTVPVSGMITIPAASLAGAQIVQTGANTNTTSSGQGTVTVTLPVAGNVVNSGGMVMMVP
SQ GAGSVPAIQRIPLPGAEMLEEEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHE
SQ SRHRHAMARKRGEGGRFFSPKEKDSPHMQDPNQADEEAMTQIIRVS
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SC Swiss-Prot#P23708-1
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FT 2 327 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 259 320 
SM00521; CBF.
FT 261 317 
PF02045; CCAAT-binding transcription factor (CBF-B/N.
FT 265 281 
putative subunit association domain (homology to T00349 [3].
FT 297 317 
putative DNA binding domain (homology to T00349 [3].
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SF (all features for 346 AA form);
SF glutamine-rich region;
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FF binds to Y-box elements of MHC class II genes;
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IN T01263 hap3; fission yeast, Schizosaccharomyces pombe.
IN T00350 Hap3p; yeast, Saccharomyces cerevisiae.
IN T00351 Hap4p; yeast, Saccharomyces cerevisiae.
IN T00087 NF-YB; rat, Rattus norvegicus.
IN T00154 NF-YB; human, Homo sapiens.
IN T00616 NF-YB; mouse, Mus musculus.
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MX M02106 V$NFYA_Q5.
MX M00209 V$NFY_C.
MX M07302 V$NFY_Q3.
MX M00185 V$NFY_Q6.
MX M00775 V$NFY_Q6_01.
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BS R16632.
BS R16970.
BS R73333.
BS R22768.
BS R16982.
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DR TRANSPATH: MO000046028.
DR TRANSCOMPEL: C00211.
DR EMBL: M86214; MMNFYA1.
DR EMBL: M86215; MMNFYAB.
DR EMBL: X55315; MMNFYA.
DR UniProtKB: P23708-1;
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RN [1]; RE0000447.
RX PUBMED: 1698608.
RA Hooft van Huijsduijnen R., Li X. Y., Black D., Matthes H., Benoist C., Mathis D.
RT Co-evolution from yeast to mouse: cDNA cloning of the two NF-Y (CP-1/CBF) subunits
RL EMBO J. 9:3119-3127 (1990).
RN [2]; RE0003045.
RX PUBMED: 1577736.
RA Li X. Y., Hooft van Huijsduijnen R., Mantovani R., Benoist C., Mathis D.
RT Intro-exon organization of the NF-Y genes. Tissue-specific splicing modifies an activation domain
RL J. Biol. Chem. 267:8984-8990 (1992).
RN [3]; RE0017971.
RX PUBMED: 9662544.
RA Edwards D., Murray J. A., Smith A. G.
RT Multiple genes encoding the conserved CCAAT-box transcription factor complex are expressed in Arabidopsis.
RL Plant Physiol. 117:1015-1022 (1998).
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