AC T00800
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ID T00800
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DT 15.04.1993 (created); ewi.
DT 21.01.2011 (updated); pum.
CO Copyright (C), QIAGEN.
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FA txnip
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SY AT1G55520; ATTBP2; T5A14.8; T5A14_8; TATA binding protein 2; TATA-binding protein 2; TATA-box binding protein; TBP-2; TFIID-2.
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OS thale cress, Arabidopsis thaliana
OC eukaryota; viridiplantae; embryobionta; magnoliophyta; magnoliopsida; dilleniidae; capparales; brassicaceae
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GE G006968 TBP2.
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CL C0082; TATA; P4.6.1.0.1.
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SF basic region;
SF sigma homology region;
SF conserved part exhibits 82% sequence identity with human TBP [2];
SF the preformed TBP-TATA box complex is recognized by TFIIB forming protein-protein as well as protein-DNA contacts [3];
SF TFIIB contacts the C-terminal "stirrup" of the TBP "saddle" [3] [4];
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CP ubiquitous.
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FF binds to and activates transcription through the TATA box [1];
FF TBP-TFIID interaction is dispensable in basal transcription in vivo [9];
FF TBP-TFIID interaction is required for transcription activated by single activation domains [9];
FF complex promoters show much less dependence on the TBP-TFIIB interaction [9];
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IN T04365 GF14; thale cress, Arabidopsis thaliana.
IN T04454 GT-1; thale cress, Arabidopsis thaliana.
IN T02229 TFIIA-L; thale cress, Arabidopsis thaliana.
IN T02230 TFIIA-S; thale cress, Arabidopsis thaliana.
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DR UniProtKB: P28148;
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RN [1]; RE0001878.
RX PUBMED: 2197561.
RA Gasch A., Hoffmann A., Horikoshi M., Roeder R. G., Chua N.-H.
RT Arabidopsis thaliana contains two gene for TFIID
RL Nature 346:390-394 (1990).
RN [2]; RE0001879.
RX PUBMED: 2374612.
RA Hoffmann A., Sinn E., Yamamoto T., Wang J., Roy A., Horikoshi M., Roeder R. G.
RT Highly conserved core domain and unique N terminus with presumptive regulatory motifs in a human TATA factor (TFIID)
RL Nature 346:387-390 (1990).
RN [3]; RE0005519.
RX PUBMED: 7675079.
RA Nikolov D. B., Chen H., Halay E. D., Usheva A. A., Hisatake K., Lee D. K., Roeder R. G., Burley S. K.
RT Crystal structure of a TFIIB-TBP-TATA-element ternary complex
RL Nature 377:119-128 (1995).
RN [4]; RE0005520.
RX PUBMED: 7637813.
RA Lee S., Hahn S.
RT Model for binding of transcription factor TFIIB to the TBP-DNA complex
RL Nature 376:609-612 (1995).
RN [5]; RE0005521.
RX PUBMED: 7634102.
RA Nikolov D. B., Burley S. K.
RT 2.1 A resolution refined structure of a TATA box-binding protein (TBP)
RL Nat. Struct. Biol. 1:621-637 (1994).
RN [6]; RE0005522.
RX PUBMED: 1436073.
RA Nikolov D. B., Hu S. H., Lin J., Gasch A., Hoffmann A., Horikoshi M., Chua N. H., Roeder R. G., Burley S. K.
RT Crystal structure of TFIID TATA-box binding protein
RL Nature 360:40-46 (1992).
RN [7]; RE0005523.
RX PUBMED: 7634103.
RA Kim J. L., Burley S. K.
RT 1.9 A resolution refined structure of TBP recognizing the minor groove of TATAAAAG
RL Nat. Struct. Biol. 1:638-653 (1994).
RN [8]; RE0005524.
RX PUBMED: 8413605.
RA Kim J. L., Nikolov D. B., Burley S. K.
RT Co-crystal structure of TBP recognizing the minor groove of a TATA element
RL Nature 365:520-527 (1993).
RN [9]; RE0017023.
RX PUBMED: 10634912.
RA Pan S., Czarnecka-Verner E., Gurley W. B.
RT Role of the TATA binding protein-transcription factor IIB interaction in supporting basal and activated transcription in plant cells
RL Plant Cell 12:125-136 (2000).
RN [10]; RE0052327.
RX PUBMED: 9801140.
RA Reindl A., Schoffl F.
RT Interaction between the Arabidopsis thaliana heat shock transcription factor HSF1 and the TATA binding protein TBP.
RL FEBS Lett. 436:318-322 (1998).
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