AC T01041
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ID T01041
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DT 21.02.1994 (created); ewi.
DT 03.03.2005 (updated); elf.
CO Copyright (C), QIAGEN.
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FA HSF
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SY HSF.
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OS clawed frog, Xenopus laevis
OC eukaryota; animalia; metazoa; chordata; vertebrata; amphibia; lissamphibia; anura; archeobatrachia; pipoidea; pipidae
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SZ 451 AA; 49.5 kDa (cDNA) (calc.).
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SQ MDPHGTCGGSNVPAFLAKLWTLVEDPDTDPLICWSPEGNSFHVFDQGQFAKEVLPKYFKH
SQ NNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPYFIRGQEQLLENIKRKVNTMS
SQ ATKSDEVKVRQDSVGKLISDVQSMKGKQESIDGRLLSMKHENEALWREVASLRQKHTQQQ
SQ KVVNKLIQFLVSLVQSNRILGVKRKIPLMLNDSSTGHSPPKYSRQYSLEHVPSSTSYPVS
SQ GFTDSSAGPIISDVTELPESSPSPSPCPSLEASPSPVILIKTEPLTPSQSPEQSPAPPKL
SQ DDTPISPSTFIDSILLETETSVCPGGNKNDEMSESHPPEPCLSVACLDNISLSRQMSEVS
SQ RLFPTSCSSVPGRAEPPGLDMAVAELNDHVDNIDFNLDTLQNLLNGQSFSVDTSALMDLF
SQ SPSLGIPDLSLPDPDSSLASVSSTPIYTCVV
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SC Swiss-Prot#P41154-1
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FT 11 115 SM00415; HSF.
FT 13 208 PF00447; HSF-type DNA-binding.
FT 15 82 PS50140; HSF_ETS.
FT 236 448 PF06546; Vertebrate heat shock transcription fact.
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FF induced by heat shock (e. g., 30 min, 33C) [5];
FF increases in late blastula during embryogenesis [1];
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IN T01264 HST; yeast, Kluyveromyces lactis.
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MX M00641 V$HSF_Q6.
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BS R02181.
BS R03623.
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DR TRANSPATH: MO000045851.
DR EMBL: L36924; XLHSF.
DR UniProtKB: P41154-1;
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RN [1]; RE0000296.
RX PUBMED: 2133546.
RA Ovsenek N., Heikkila J. J.
RT DNA sequence-specific binding activity of the heat-shock transcription factor is heat-inducible before the midblastula transition of early Xenopus development
RL Development 110:427-433 (1990).
RN [2]; RE0005273.
RX PUBMED: 6814763.
RA Pelham H. R. B.
RT A regulatory upstream promoter element in the Drosophila hsp70 heat-shock gene
RL Cell 30:517-528 (1982).
RN [3]; RE0005274.
RX PUBMED: 6327271.
RA Pelham H. R. B., Bienz M.
RT A synthetic heat-shock promoter element confers heat-inducibility on the herpes simplex virus thymidine kinase gene
RL EMBO J. 1:1473-1477 (1982).
RN [4]; RE0005276.
RX PUBMED: 3085957.
RA Bienz M., Pelham H. R. B.
RT Heat shock regulatory elements function as an inducible enhancer in teh Xenopus hsp70 gene and when linked to a heterologous promoter
RL Cell 45:753-760 (1986).
RN [5]; RE0005277.
RX PUBMED: 8441385.
RA Sarge K. D., Murphy S. P., Morimoto R. I.
RT Activation of heat shock gene transcription by heat shockfactor 1 involves oligomerization, acquisition of DNA-binding activity, and nuclear localization and can occur in the absence of stress
RL Mol. Cell. Biol. 13:1392-1407 (1993).
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