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TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN


AC T01387 XX ID T01387 XX DT 08.12.1994 (created); ewi. DT 27.03.2015 (updated); asv. CO Copyright (C), QIAGEN. XX FA CHOP-10 XX SY C/EBP homologous protein 10; CEBPZ; CHOP; CHOP-10; CHOP10; DDIT3; DNA-damage-inducible transcript 3; GADD 153; GADD153; growth arrest and DNA-damage-inducible gene 153; MGC4154. XX OS human, Homo sapiens OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates XX GE G009609 DDIT3; HGNC: DDIT3. XX CL C0008; bZIP; 1.1.8.1.6. XX SF the oncogenic variant TLS-CHOP has a large N-terminal extension; XX CP adipocytes [2]. XX FF inducible by calcium ions [1]; FF causes cell growth arrest at/around the G1/S checkpoint [2]; FF an oncogenic variant, TLS-CHOP, is associated with adipose tissue myxoid liposarcoma; FF it is not capable to induce growth arrest [2]; XX IN T18809 B-ATF; human, Homo sapiens. IN T00105 C/EBPalpha; human, Homo sapiens. IN T04883 C/EBPepsilon; human, Homo sapiens. IN T04884 C/EBPgamma; human, Homo sapiens. IN T04875 DBP; human, Homo sapiens. XX MX M00249 V$CHOP_01. XX BS R04603. BS R42132. BS R70462. BS R63595. BS R63632. BS R65107. BS R25985. BS R64741. BS R03475. XX DR TRANSPATH: MO000020832. DR UniProtKB: P35638; GA15_HUMAN. XX RN [1]; RE0001111. RX PUBMED: 1400365. RA Bartlett J. D., Luethy J. D., Carlson S. G., Sollott S. J., Holbrook N. J. RT Calcium ionophore A23187 induces expression of the growth arrest and DNA damage inducible CCAAT/enhancer-binding protein (C/EBP)-related gene gadd153 RL J. Biol. Chem. 267:20465-20470 (1992). RN [2]; RE0007049. RX PUBMED: 8125258. RA Barone M. V., Crozat A., Tabaee A., Philipson L., Ron D. RT CHOP (GADD153) and its oncogenic variant, TLS-CHOP, have opposing effects on the induction of G1/S arrest RL Genes Dev. 15:453-464 (1995). RN [3]; RE0049681. RX PUBMED: 15897896. RA Benali-Furet N. L., Chami M., Houel L., De Giorgi F., Vernejoul F., Lagorce D., Buscail L., Bartenschlager R., Ichas F., Rizzuto R., Paterlini-Brechot P. RT Hepatitis C virus core triggers apoptosis in liver cells by inducing ER stress and ER calcium depletion. RL Oncogene 24:4921-4933 (2005). RN [4]; RE0066024. RX PUBMED: 15308577. RA Gery S., Park D. J., Vuong P. T., Chih D. Y., Lemp N., Koeffler H. P. RT Retinoic acid regulates C/EBP homologous protein expression (CHOP), which negatively regulates myeloid target genes. RL Blood 104:3911-3917 (2004). XX //