AC T01400
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ID T01400
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DT 10.12.1994 (created); ewi.
DT 29.07.2014 (updated); sla.
CO Copyright (C), QIAGEN.
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FA c-Ets-1B
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SY c-Ets-1B; Ets-1 deltaVII.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G000217 ETS1; HGNC: Ets1.
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CL C0016; ETS; 3.5.2.1.1.2.
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SZ 354 AA; 40.8 kDa (cDNA) (calc.), 39 kDa, 42 kDa (SDS)
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SQ MKAAVDLKPTLTIIKTEKVDLELFPSPDMECADVPLLTPSSKEMMSQALKATFSGFTKEQ
SQ QRLGIPKDPRQWTETHVRDWVMWAVNEFSLKGVDFQKFCMNGAALCALGKDCFLELAPDF
SQ VGDILWEHLEILQKEDVKPYQVNGVNPAYPESRYTSDYFISYGIEHAQCVPPSEFSEPSF
SQ ITESYQTLHPISSEELLSLKYENDYPSVILRDPLQTDTLQNDYFAIKQEVVTPDNMCMGR
SQ TSRGSGPIQLWQFLLELLTDKSCQSFISWTGDGWEFKLSDPDEVARRWGKRKNKPKMNYE
SQ KLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQSLLGYTPEELHAMLDVKPDADE
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SC Swiss-Prot#P14921-2
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FT 53 136 
PF02198; Sterile alpha motif (SAM)/Pointed domain.
FT 53 136 
SM00251; SAM2_3.
FT 247 330 
PF00178; Ets-domain.
FT 247 332 
SM00413; etsneu2.
FT 248 328 
PS50061; ETS_DOMAIN_3.
FT 250 318 
PS50140; HSF_ETS.
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SF alternative splice variant is c-Ets-1 T00112;
SF inhibitory region is missing in this splice variant [1];
SF isoform 48 kDa may be due to SH-modification [2];
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MX M00032 V$CETS1P54_01.
MX M00074 V$CETS1P54_02.
MX M01078 V$CETS1P54_03.
MX M01870 V$CETS1_Q6.
MX M00339 V$ETS1_B.
MX M08881 V$ETSLIKE_Q4.
MX M00340 V$ETS_B.
MX M00771 V$ETS_Q4.
MX M00971 V$ETS_Q6.
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BS R04050.
BS R04051.
BS R04052.
BS R04053.
BS R01224.
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DR TRANSPATH: MO000025648.
DR EMBL: X14798;
DR UniProtKB: P14921-2;
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RN [1]; RE0000799.
RX PUBMED: 1592263.
RA Wasylyk C., Kerckaert J.-P., Wasylyk B.
RT A novel modulator domain of Ets transcription factors
RL Genes Dev. 6:965-974 (1992).
RN [2]; RE0001113.
RX PUBMED: 1517230.
RA Fisher R. J., Koizumi S., Kondoh A., Mariano J. M., Mavrothalassitis G., Bhat N. K., Papas T. S.
RT Human Ets1 oncoprotein
RL J. Biol. Chem. 267:17957-17965 (1992).
RN [3]; RE0005311.
RX PUBMED: 2030910.
RA Jorcyk C. L., Watson D. K., Mavrothalassitis G. J., Papas T. S.
RT The human ETS1 gene: genomic structure, promoter characterization and alternative splicing
RL Oncogene 6:523-532 (1991).
RN [4]; RE0005312.
RX PUBMED: 3060801.
RA Reddy E. S. P., Rao V. N.
RT Structure, expression and alternative splicing of the human c-ets-1 proto-oncogene
RL Oncogene 3:239-246 (1988).
RN [5]; RE0007147.
RX PUBMED: 8195127.
RA Uchijima M., Sato H., Fujii M., Seiki M.
RT Tax proteins of human T-cell leukemia virus type 1 and 2 induce expression of the gene encoding erythroid-potentiating activity (Tissue inhibitor of metalloproteinases-1, TIMP-1).
RL J. Biol. Chem. 269:14946-14950 (1994).
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