
AC   T01417
XX
ID   T01417
XX
DT   11.12.1994 (created); ewi.
DT   20.03.2013 (updated); uat.
CO   Copyright (C), QIAGEN.
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FA   TEL1
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SY   ETS translocation variant 6; ETS-related protein Tel1; ETV6; tel; Transcription factor ETV6.
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OS   human, Homo sapiens
OC   eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE   G006041 ETV6; HGNC: ETV6.
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CL   C0016; ETS; 3.5.2.6.1.
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FF   part of the chromosomal translocation t(5;
FF   12)(q33;
FF   p13) fusing the putative HLH domain of tel to the tyrosine kinase domain of PDGF receptor beta early in transition of CMML (chronic myelomonocytic leukemia) to AML (acute myelogenous leukemia) [1];
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IN   T14458 STAT3; Mammalia.
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MX   M00971 V$ETS_Q6.
MX   M03985 V$ETV6_02.
MX   M02070 V$TEL1_02.
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BS   R73632.
BS   R73684.
BS   R42148.
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DR   TRANSPATH: MO000025656.
DR   UniProtKB: P41212;
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RN   [1]; RE0000282.
RX   PUBMED: 8168137.
RA   Golub T. R., Barker G. F., Lovett M., Gilliland D. G.
RT   Fusion of PDGf receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation
RL   Cell 77:307-316 (1994).
RN   [2]; RE0047428.
RX   PUBMED: 15229229.
RA   Schick N., Oakeley E. J., Hynes N. E., Badache A.
RT   TEL/ETV6 is a signal transducer and activator of transcription 3 (Stat3)-induced repressor of Stat3 activity.
RL   J. Biol. Chem. 279:38787-38796 (2004).
RN   [3]; RE0052481.
RX   PUBMED: 12590135.
RA   Petrie K., Guidez F., Howell L., Healy L., Waxman S., Greaves M., Zelent A.
RT   The histone deacetylase 9 gene encodes multiple protein isoforms.
RL   J. Biol. Chem. 278:16059-16072 (2003).
XX
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