AC T01432
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ID T01432
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DT 10.04.1995 (created); ewi.
DT 18.01.2016 (updated); sup.
CO Copyright (C), QIAGEN.
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FA c-MAF
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SY (proto-oncogene C-MAF); c-maf; MAF; MAF2.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G009013 Maf.
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CL C0008; bZIP; 1.1.3.1.1.
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SF the region which is essential for trans-activation may contribute to DNA-binding [2];
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CP kidney, brain, gut, lung, mesenterium, testis, ovary [1], Th2 cells [3] [1] [3]; Peritoneal macrophage, macrophage + LPS, macrophage + Bacterial DNA [4].
CN Th1 cells, B cells [3].
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FF transcriptional activator [1] [2];
FF involved in Th2-specific gene activation, synergizing with NF-ATp T01944 [3];
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MX M01070 V$CMAF_01.
MX M01228 V$CMAF_02.
MX M03816 V$CMAF_Q5.
MX M07296 V$MAF_Q4.
MX M00648 V$MAF_Q6.
MX M00983 V$MAF_Q6_01.
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BS R20364.
BS R20365.
BS R20366.
BS R20369.
BS R65637.
BS R65638.
BS R65639.
BS R19684.
BS R19686.
BS R19688.
BS R30215.
BS R33518.
BS R65423.
BS R65425.
BS R65433.
BS R65435.
BS R65447.
BS R65448.
BS R65451.
BS R65570.
BS R04775.
BS R73943.
BS R20765.
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DR TRANSPATH: MO000008871.
DR TRANSCOMPEL: C00162.
DR UniProtKB: P54843;
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RN [1]; RE0004906.
RX PUBMED: 7935473.
RA Kataoka K., Fujiwara K. T., Noda M., Nishizawa M.
RT MafB, a new Maf family transcription activator that can associate with Maf and Fos but not with Jun
RL Mol. Cell. Biol. 14:7581-7591 (1994).
RN [2]; RE0004907.
RX PUBMED: 7799931.
RA Kurschner C., Morgan J. I.
RT The maf proto-oncogene stimulates transcription from multiple sites in a promoter that directs Purkinje neuron-specific gene expression
RL Mol. Cell. Biol. 15:246-254 (1995).
RN [3]; RE0006606.
RX PUBMED: 8674125.
RA Ho I-C., Hodge M. R., Rooney J. W., Glimcher L. H.
RT The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4
RL Cell 85:973-983 (1996).
RN [4]; RE0053838.
RX PUBMED: 15372110.
RA Sugimoto K., Ohata M., Miyoshi J., Ishizaki H., Tsuboi N., Masuda A., Yoshikai Y., Takamoto M., Sugane K., Matsuo S., Shimada Y., Matsuguchi T.
RT A serine/threonine kinase, Cot/Tpl2, modulates bacterial DNA-induced IL-12 production and Th cell differentiation.
RL J. Clin. Invest. 114:857-866 (2004).
RN [5]; RE0066522.
RX PUBMED: 17493607.
RA Simirskii V. N., Wang Y., Duncan M. K.
RT Conditional deletion of beta1-integrin from the developing lens leads to loss of the lens epithelial phenotype.
RL Dev. Biol. 306:658-668 (2007).
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