TRANSFAC-Logo

TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN


AC T01433 XX ID T01433 XX DT 10.04.1995 (created); ewi. DT 05.03.2007 (updated); mkl. CO Copyright (C), QIAGEN. XX FA MafB XX SY MAFB. XX OS chick, Gallus gallus OC eukaryota; animalia; metazoa; chordata; vertebrata; aves; neornithes; neognathae; galliformes; phasianidae XX GE G037191 MAFB. XX CL C0008; bZIP; 1.1.3.1.3. XX SF no heterodimerization with c-Jun (contrast to v-Maf) [1]; SF binds to TRE-type and CRE-type elements with equal affinity [1]; SF DNA-binding specificity differs from that of AP-1 in that it also recognizes tTactAa [1]; XX CP brain, thymus, lung, gut, mesenterium, spleen, kidney, ovary, bursa (high); stomach, liver, testis (marginal) [1]. CN pancreas [1]. XX FF relatively weak transcriptional activator (compared with v-Maf), but nearly the same transforming activity [1]; FF interacts with the DNA-binding domain of c-Ets-1 thereby repressing trans-activation by this factor [2]; FF therefore, MafB inhibits erythroid differentiation [2]; XX IN T00114 c-Ets-1 54; chick, Gallus gallus. IN T00125 c-Fos; chick, Gallus gallus. IN T01433 MafB; chick, Gallus gallus. XX MX M01227 V$MAFB_01. MX M03830 V$MAFB_Q4. MX M08888 V$MAFB_Q4_01. MX M07296 V$MAF_Q4. MX M00983 V$MAF_Q6_01. XX BS R18177. BS R18188. XX DR TRANSPATH: MO000025664. DR UniProtKB: Q90888; Q90888. XX RN [1]; RE0004906. RX PUBMED: 7935473. RA Kataoka K., Fujiwara K. T., Noda M., Nishizawa M. RT MafB, a new Maf family transcription activator that can associate with Maf and Fos but not with Jun RL Mol. Cell. Biol. 14:7581-7591 (1994). RN [2]; RE0004908. RX PUBMED: 8620536. RA Sieweke M. H., Tekotte H., Frampton J., Graf T. RT MafB is an interaction partner and repressor of Ets-1 that inhibits erythroid differentiation RL Cell 85:49-60 (1996). XX //