AC T01448
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ID T01448
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DT 18.04.1995 (created); ewi.
DT 09.01.2007 (updated); sou.
CO Copyright (C), QIAGEN.
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FA Tal1-PP22
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G001188 TAL1; HGNC: TAL1.
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CL C0010; bHLH.
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SZ 156 AA; 16.5 kDa (cDNA) (calc.), 22 kDa (SDS)
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SQ MEITDGPHTKVVRRIFTNSRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKY
SQ INFLAKLLNDQEEEGTQRAKTGKDPVVGAGGGGGGGGGGAPPDDLLQDVLSPNSSCGSSL
SQ DGAASPDSYTEEPAPKHTARSLHPAMLPAADGAGPR
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SC edited Swiss-Prot #P17542
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FT 13 65 PF00010; Helix-loop-helix DNA-binding domain.
FT 13 65 PS50888; HLH.
FT 18 70 SM00353; finulus.
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SF alternative translation initiation product of TAL-1;
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FF tal-1 gene rearrangements in patients with T-cell acute lymphoblastic leukemia;
FF does not bind to DNA since it does not form homodimers;
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IN T00207 E47; human, Homo sapiens.
IN T00433 ITF-2; human, Homo sapiens.
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MX M01034 V$EBOX_Q6_01.
MX M00066 V$TAL1ALPHAE47_01.
MX M00065 V$TAL1BETAE47_01.
MX M00070 V$TAL1BETAITF2_01.
MX M01591 V$TAL1_01.
MX M00993 V$TAL1_Q6.
MX M03804 V$TAL1_Q6_01.
MX M07469 V$TALLIKE_Q6.
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BS R04157.
BS R04158.
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DR TRANSPATH: MO000019583.
DR UniProtKB: P17542-3;
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RN [1]; RE0002932.
RX PUBMED: 8289805.
RA Hsu H.-L., Huang L., Tsan J. T., Funk W., Wright W. E., Hu J.-S., Kingston R. E., Baer R.
RT Preferred sequences for DNA recognition by the TAL1 helix-loop-helix proteins
RL Mol. Cell. Biol. 14:1256-1265 (1994).
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