AC T01470
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ID T01470
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DT 02.05.1995 (created); ewi.
DT 02.04.2009 (updated); pum.
CO Copyright (C), QIAGEN.
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FA Ikaros-isoform2
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SY 5832432G11Rik; hlk-1; Ikaros; LyF-1; zinc finger protein, subfamily 1A, 1 (Ikaros); ZNFN1A1.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G005193 Ikzf1.
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CL C0001; CH.
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SZ 307 AA; 34.0 kDa (cDNA) (calc.).
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SQ MDVDEGQDMSQVSGKESPPVSDTPDEGDEPMPVPEDLSTTSGAQQNSKSDRGVAYGADGF
SQ RDFHAIISDRGMDKCLSDMPYDSANYEKEDMMTSHVMDQAINNAINYLGAESLRPLVQTP
SQ PGSSEVVPVISSMYQLHKPPSDGPPRSNHSAQDAVDNLLLLSKAKSVSSEREASPSNSCQ
SQ DSTDTESNAEEQRSGLIYLTNHINPHARNGLALKEEQRAYEVLRAASENSQDAFRVVSTS
SQ GEQLKVYKCEHCRVLFLDHVMYTIHMGCHGCHGFRDPFECNMCGYHSQDRYEFSSHITRG
SQ EHRYHLS
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SC Swiss-prot#Q03267-3
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SF 3+2 zinc finger;
SF encoded by ikaros gene exons 1,2,4-7 [1];
SF this form is mentioned as LyF-1 isoform VI in [2];
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CP early lymphocytes, mature T cells, corpus striatum, early fetal liver, maturing thymus, postnatal spleen.
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FF may play a critical role in development of the lymphocyte lineage(s) [1];
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IN T09170 CtBP1-isoform1; human, Homo sapiens.
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MX M00086 V$IK1_01.
MX M00087 V$IK2_01.
MX M00088 V$IK3_01.
MX M07260 V$IK_Q5_01.
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BS R04204.
BS R04205.
BS R04206.
BS R04207.
BS R04208.
BS R04209.
BS R04210.
BS R04211.
BS R14773.
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DR TRANSPATH: MO000025692.
DR EMBL: L03547;
DR UniProtKB: Q03267-3;
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RN [1]; RE0002963.
RX PUBMED: 7969165.
RA Molnar A., Georgopoulos K.
RT The Ikaros gene encodes a family of functionally diverse zinc finger DNA-binding proteins
RL Mol. Cell. Biol. 14:8292-8303 (1994).
RN [2]; RE0006501.
RX PUBMED: 7935426.
RA Hahm K., Ernst P., Lo K., Kim G. S., Turck C., Smale S. T.
RT The lymphoid transcrption factor LyF-1 is encoded by specific, alternatively spliced mRNAs derived from the Ikaros gene
RL Mol. Cell. Biol. 14:7111-7123 (1994).
RN [3]; RE0024292.
RX PUBMED: 1439790.
RA Georgopoulos K., Moore D. D., Derfler B.
RT Ikaros, an early lymphoid-specific transcription factor and a putative mediator for T cell commitment.
RL Science 258:808-812 (1992).
RN [4]; RE0026561.
RX PUBMED: 10766745.
RA Koipally J., Georgopoulos K.
RT Ikaros interactions with CtBP reveal a repression mechanism that is independent of histone deacetylase activity
RL J. Biol. Chem. 275:19594-602 (2000).
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