AC T09170
XX
ID T09170
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DT 01.08.2006 (created); jag.
DT 04.09.2014 (updated); pos.
CO Copyright (C), QIAGEN.
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FA CtBP1-isoform1
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SY C-terminal binding protein; C-terminal binding protein 1.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G004732 CTBP1; HGNC: CTBP1.
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SZ 440 AA; 47.5 kDa (cDNA) (calc.).
XX
SQ MGSSHLLNKGLPLGVRPPIMNGPLHPRPLVALLDGRDCTVEMPILKDVATVAFCDAQSTQ
SQ EIHEKVLNEAVGALMYHTITLTREDLEKFKALRIIVRIGSGFDNIDIKSAGDLGIAVCNV
SQ PAASVEETADSTLCHILNLYRRATWLHQALREGTRVQSVEQIREVASGAARIRGETLGII
SQ GLGRVGQAVALRAKAFGFNVLFYDPYLSDGVERALGLQRVSTLQDLLFHSDCVTLHCGLN
SQ EHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFS
SQ QGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIRRAITGRIPDSLKNCVNKDHLTAAT
SQ HWASMDPAVVHPELNGAAYRYPPGVVGVAPTGIPAAVEGIVPSAMSLSHGLPPVAHPPHA
SQ PSPGQTVKPEADRDHASDQL
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SC translated from EMBL #U37408
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FT 29 122 
PF00389; D-isomer specific 2-hydroxyacid dehydrog.
FT 88 371 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 133 313 
PF02826; D-isomer specific 2-hydroxyacid dehydrog.
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IN T05220 Evi-1; human, Homo sapiens.
IN T25625 hdac2; human, Homo sapiens.
IN T15475 Ikaros-1; Mammalia.
IN T01469 Ikaros-isoform1; mouse, Mus musculus.
IN T09490 Ikaros-isoform1; human, Homo sapiens.
IN T01470 Ikaros-isoform2; mouse, Mus musculus.
IN T01471 Ikaros-isoform3; mouse, Mus musculus.
IN T00479 Ikaros; mouse, Mus musculus.
IN T14622 sin3a; human, Homo sapiens.
IN T10218 TGIF1-isoform1; mouse, Mus musculus.
IN T09151 TGIF2-isoform1; human, Homo sapiens.
IN T04076 TGIF; human, Homo sapiens.
XX
BS R63390.
BS R63603.
BS R63635.
XX
DR TRANSPATH: MO000084023.
DR EMBL: AF091555; AF091555.
DR EMBL: BC011655; BC011655.
DR EMBL: U37408; HS37408.
DR UniProtKB: Q13363; CTB1_HUMAN.
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RN [1]; RE0026561.
RX PUBMED: 10766745.
RA Koipally J., Georgopoulos K.
RT Ikaros interactions with CtBP reveal a repression mechanism that is independent of histone deacetylase activity
RL J. Biol. Chem. 275:19594-602 (2000).
RN [2]; RE0027320.
RX PUBMED: 10995736.
RA Melhuish T. A., Wotton D.
RT The interaction of the carboxyl terminus-binding protein with the smad corepressor TGIF is disrupted by a holoprosencephaly mutation in TGIF
RL J. Biol. Chem. 275:39762-6 (2000).
RN [3]; RE0047925.
RX PUBMED: 11427533.
RA Melhuish T. A., Gallo C. M., Wotton D.
RT TGIF2 interacts with histone deacetylase 1 and represses transcription.
RL J. Biol. Chem. 276:32109-32114 (2001).
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