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TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN


AC T09490 XX ID T09490 XX DT 16.10.2006 (created); apk. DT 20.11.2008 (updated); mka. CO Copyright (C), QIAGEN. XX FA Ikaros-isoform1 XX SY Ik-1; Ik1; Ikaros 1; LyF-1; lymphoid transcription factor 1. XX OS human, Homo sapiens OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates XX GE G004705 IKZF1; HGNC: IKZF1. XX CL C0001; CH; 2.3.4.4.1.1. XX SZ 519 AA; 57.5 kDa (cDNA) (calc.). XX SQ MDADEGQDMSQVSGKESPPVSDTPDEGDEPMPIPEDLSTTSGGQQSSKSDRVVASNVKVE SQ TQSDEENGRACEMNGEECAEDLRMLDASGEKMNGSHRDQGSSALSGVGGIRLPNGKLKCD SQ ICGIICIGPNVLMVHKRSHTGERPFQCNQCGASFTQKGNLLRHIKLHSGEKPFKCHLCNY SQ ACRRRDALTGHLRTHSVGKPHKCGYCGRSYKQRSSLEEHKERCHNYLESMGLPGTLYPVI SQ KEETNHSEMAEDLCKIGSERSLVLDRLASNVAKRKSSMPQKFLGDKGLSDTPYDSSASYE SQ KENEMMKSHVMDQAINNAINYLGAESLRPLVQTPPGGSEVVPVISPMYQLHKPLAEGTPR SQ SNHSAQDSAVENLLLLSKAKLVPSEREASPSNSCQDSTDTESNNEEQRSGLIYLTNHIAP SQ HARNGLSLKEEHRAYDLLRAASENSQDALRVVSTSGEQMKVYKCEHCRVLFLDHVMYTIH SQ MGCHGFRDPFECNMCGYHSQDRYEFSSHITRGEHRFHMS XX SC translated from EMBL #U40462 XX FT 117 139 SM00355; c2h2final6. FT 117 144 PS50157; ZINC_FINGER_C2H2_2. FT 145 167 PF00096; zf-C2H2. FT 145 167 SM00355; c2h2final6. FT 145 172 PS50157; ZINC_FINGER_C2H2_2. FT 173 195 PF00096; zf-C2H2. FT 173 195 SM00355; c2h2final6. FT 173 200 PS50157; ZINC_FINGER_C2H2_2. FT 201 224 PF00096; zf-C2H2. FT 201 224 SM00355; c2h2final6. FT 201 229 PS50157; ZINC_FINGER_C2H2_2. FT 462 484 SM00355; c2h2final6. FT 490 514 SM00355; c2h2final6. XX FF Ikaros-isoform1 plays a significant positive role in STAT4 gene expression [3]; XX IN T09170 CtBP1-isoform1; human, Homo sapiens. XX MX M00086 V$IK1_01. MX M00087 V$IK2_01. MX M00088 V$IK3_01. MX M07260 V$IK_Q5_01. XX DR TRANSPATH: MO000089251. DR EMBL: U40462; DR UniProtKB: Q13422-1; XX RN [1]; RE0013555. RX PUBMED: 8964602. RA Nietfeld W., Meyerhans A. RT Cloning and sequencing of hIk-1, a cDNA encoding a human homologue of mouse Ikaros/LyF-1. RL Immunol. Lett. 49:139-141 (1996). RN [2]; RE0026561. RX PUBMED: 10766745. RA Koipally J., Georgopoulos K. RT Ikaros interactions with CtBP reveal a repression mechanism that is independent of histone deacetylase activity RL J. Biol. Chem. 275:19594-602 (2000). RN [3]; RE0048537. RX PUBMED: 16081070. RA Yap W. H., Yeoh E., Tay A., Brenner S., Venkatesh B. RT STAT4 is a target of the hematopoietic zinc-finger transcription factor Ikaros in T cells. RL FEBS Lett. 579:4470-4478 (2005). XX //