AC T01523
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ID T01523
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DT 13.06.1995 (created); ewi.
DT 08.04.2013 (updated); spk.
CO Copyright (C), QIAGEN.
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FA RelA-p65-delta
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SY NFKB3; p65delta; RELA; v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian).
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G004622 RELA; HGNC: RELA.
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CL C0020; Rel; 6.1.1.2.1.2.
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SZ 541 AA; 59.1 kDa (cDNA) (calc.).
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SQ MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT
SQ IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC
SQ VKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLP
SQ HPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKGWEARGSFSQADVHRQVAI
SQ VFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEEKRKRTYETFK
SQ SIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINYDEFPTMVFPS
SQ GQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQAVAPPAPKPTQ
SQ AGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQGIPVAPHTTE
SQ PMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADMDFSALLSQIS
SQ S
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SC edited Swiss-Prot #Q04206
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FT 16 190 
PS50254; REL_2.
FT 21 186 
PF00554; Rel homology domain (RHD).
FT 193 279 
SM00429; iptmega2.
FT 194 279 
PF01833; IPT/TIG domain.
FT 405 540 
corresponds to the transcription activation domain of RelA [1].
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SF several proline-rich regions;
SF alternative splice variant of RelA (p65);
SF no homodimerization or heterodimerization with p50;
SF weak heterodimerization with RelA;
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CP (Jurkat).
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FF greatly reduces DNA-binding by RelA;
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IN T00594 RelA-p65-isoform1; human, Homo sapiens.
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MX M00052 V$NFKAPPAB65_01.
MX M00054 V$NFKAPPAB_01.
MX M00774 V$NFKB_Q6_01.
MX M03563 V$RELA_Q6.
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DR TRANSPATH: MO000025736.
DR UniProtKB: Q04206-3;
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RN [1]; RE0003105.
RX PUBMED: 1732726.
RA Ruben S. M., Narayanan R., Klement J. F., Chen C.-H., Rosen C. A.
RT Functional characterization of the NF-kappaB p65 transcriptional activator and an alternatively spliced derivate
RL Mol. Cell. Biol. 12:444-454 (1992).
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//