AC T01620
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ID T01620
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DT 30.01.1996 (created); ewi.
DT 24.05.2011 (updated); mkl.
CO Copyright (C), QIAGEN.
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FA MASH-1
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SY ASH-1; HASH1; mammalian achaete-scute homolog 1; MASH-1.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G003960 ASCL1; HGNC: ASCL1.
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CL C0010; bHLH.
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SZ 238 AA; 25.7 kDa (cDNA) (calc.).
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SQ MESSAKMESGGAGQQPQPQPQQPFLPPAACFFATAAAAAAAAAAAAAQSAQQQQQQQQQQ
SQ QQQQAPQLRPAADGQPSGGGHKSAPKQVKRQRSSSPELMRCKRRLNFSGFGYSLPQQQPA
SQ AVARRNERERNRVKLVNLGFATLREHVPNGAANKKMSKVETLRSAVEYIRALQQLLDEHD
SQ AVSAAFQAGVLSPTISPNYSNDLNSMAGSPVSSYSSDEGSYDPLSPEEQELLDFTNWF
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SC conceptually translated from EMBL/GenBank/DDBJ #L08424
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FT 89 173 PS50888; HLH.
FT 123 173 PF00010; Helix-loop-helix DNA-binding domain.
FT 126 178 SM00353; finulus.
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SF use of a potential alternative translation initiation codon [1];
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CP some neuroendocrine cell lines, low levels in fetal brain [1].
CN adult brain, heart, kidney, liver, lung, pancreas, placenta, skeletal muscle [1].
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IN T00204 E12; human, Homo sapiens.
IN T01503 HTF4; human, Homo sapiens.
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MX M00973 V$E2A_Q6.
MX M01034 V$EBOX_Q6_01.
MX M03877 V$MASH1_Q6.
MX M07422 V$MASH1_Q6_01.
MX M08820 V$MASH1_Q6_02.
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BS R00242.
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DR TRANSPATH: MO000025808.
DR EMBL: L08424;
DR UniProtKB: P50553;
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RN [1]; RE0003627.
RX PUBMED: 8390674.
RA Ball D. W., Azzoli C. G., Baylin S. B., Chi D., Dou S., Donis-Keller H., Cumaraswamy A., Borges M., Nelkin B. D.
RT Identification of a human achaete-scute homolog highly expressed in neuroendocrine tumors
RL Proc. Natl. Acad. Sci. USA 90:5648- 5652 (1993).
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