AC T01626
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ID T01626
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DT 30.01.1996 (created); ewi.
DT 31.08.2012 (updated); jmh.
CO Copyright (C), QIAGEN.
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FA NeuroD
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SY Beta2.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G009272 Neurod1.
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CL C0010; bHLH; 1.2.3.4.1.
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SF sequence contains an additional Arg in position 57 [1];
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FF Pdx1, MafA, and Beta2 synergistically activate the insulin gene promoter in the hamster insulinoma-derived cell line In1024 [3];
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IN T08664 C/EBPalpha; Mammalia.
IN T08226 MafA; mouse, Mus musculus.
IN T02971 p107; mouse, Mus musculus.
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MX M01287 V$NEUROD_01.
MX M01288 V$NEUROD_02.
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BS R70470.
BS R70471.
BS R70472.
BS R70473.
BS R70474.
BS R70475.
BS R70476.
BS R70477.
BS R70478.
BS R70513.
BS R70514.
BS R70515.
BS R70516.
BS R70520.
BS R70522.
BS R70523.
BS R70525.
BS R70526.
BS R35229.
BS R24201.
BS R31577.
BS R40055.
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DR TRANSPATH: MO000025814.
DR TRANSCOMPEL: C00516.
DR EMBL: U28068;
DR EMBL: U28888;
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RN [1]; RE0003634.
RX PUBMED: 7754368.
RA Lee J. E., Hollenberg S. M., Snider L., Turner D. L., Lipnick N., Weintraub H.
RT Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix protein
RL Science 268:836-844 (1995).
RN [2]; RE0048167.
RX PUBMED: 15701640.
RA Batsche E., Moschopoulos P., Desroches J., Bilodeau S., Drouin J.
RT Retinoblastoma and the related pocket protein p107 act as coactivators of NeuroD1 to enhance gene transcription.
RL J. Biol. Chem. 280:16088-16095 (2005).
RN [3]; RE0048170.
RX PUBMED: 15993959.
RA Aramata S., Han S. I., Yasuda K., Kataoka K.
RT Synergistic activation of the insulin gene promoter by the beta-cell enriched transcription factors MafA, Beta2, and Pdx1.
RL Biochim. Biophys. Acta 1730:41-46 (2005).
RN [4]; RE0050079.
RX PUBMED: 17254333.
RA Calella A. M., Nerlov C., Lopez R. G., Sciarretta C., von Bohlen Und Halbach O., Bereshchenko O., Minichiello L.
RT Neurotrophin/Trk receptor signaling mediates C/EBPalpha, -beta and NeuroD recruitment to immediate-early gene promoters in neuronal cells and requires C/EBPs to induce immediate-early gene transcription.
RL Neural Develop. 2:4 (2007).
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