AC T01628
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ID T01628
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DT 30.01.1996 (created); ewi.
CO Copyright (C), QIAGEN.
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FA Ato
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SY Atonal.
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OS fruit fly, Drosophila melanogaster
OC eukaryota; animalia; metazoa; arthropoda; insecta; diptera; drosophiloidea; drosophilidae
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CL C0010; bHLH.
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SZ 312 AA; 34.1 kDa (cDNA) (calc.).
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SQ MSSSEIYRYYYKTSEDLQGFKTAAAEPYFNPMAAYNPGVTHYQFNGNTLASSSNYLSANG
SQ FISFEQASSDGWISSSPASHRSESPEYVDLNTMYNGGCNNMAQNQQYGMIMEQSVVSTAP
SQ AIPVASPPAVEVMGSSNVGTCKTIPASAAPKPKRSYTKKNQPSTTATSTPTAAAESSASV
SQ NLYTEEFQNFDFDNSALFDDSVEDDEDLMLFSGGEDFDGNDGSFDLADGENQDAAAGGSG
SQ KKRRGKQITPVVKRKRRLAANARERRRMQNLNQAFDRLRQYLPCLGNDRQLSKHETLQMA
SQ QTYISALGDLLR
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SC conceptually translated from EMBL/GenBank/DDBJ #L36646
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FT 253 308 PS50888; HLH.
FT 256 308 PF00010; Helix-loop-helix DNA-binding domain.
FT 261 312 SM00353; finulus.
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SF only distantly related to AS-C proteins (46% identity);
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CP proneural clusters, sense organ precursors of cordotonal organs [1].
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FF regulates neuroblast cell fate of cordotonal organ and R8 photoreceptor precursor cells, not of external sensory organs (contrasting to AS-C factors) [1];
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IN T01034 Da; fruit fly, Drosophila melanogaster.
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DR TRANSPATH: MO000025816.
DR EMBL: L36646;
DR FLYBASE: FBgn0010433; ato.
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RN [1]; RE0003637.
RX PUBMED: 8324823.
RA Jarman A. P., Grau Y., Jan L. Y., Jan Y. N.
RT atonal is a proneural gene that directs chordotonal organ formation in the Drosophila peripheral nervous system
RL Cell 73:1307-1321 (1993).
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