AC T01630
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ID T01630
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DT 31.01.1996 (created); ewi.
DT 02.04.2013 (updated); mkl.
CO Copyright (C), QIAGEN.
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FA Tal-2
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G009122 TAL2; HGNC: TAL2.
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CL C0010; bHLH; 1.2.3.1.2.
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SF simultaneously with the E47 interaction, Tal-2 can bind the LIM-only proteins RTBN1 (T-ALL cells) and RTBN2 (erythroid cells) [1];
SF this interaction specifically requires an intact Tal-type bHLH domain and [2];
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IN T00207 E47; human, Homo sapiens.
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MX M01034 V$EBOX_Q6_01.
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DR TRANSPATH: MO000019582.
DR UniProtKB: Q16559;
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RN [1]; RE0003639.
RX PUBMED: 1763056.
RA Xia Y., Brown L., Yang Y.-C., Tsan J. T., Siciliano M. J., Espinosa III R., Le Beau M. M., Baer R.
RT TAL2, a helix-loop-helix gene activated by the (7;9)(q34;q32) translocation in human T-cell leukemia
RL Proc. Natl. Acad. Sci. USA 88:11416-11420 (1991).
RN [2]; RE0003640.
RX PUBMED: 7957052.
RA Wadman I., Li J., Bash R. O., Forster A., Osada H., Rabbitts T. H., Baer R.
RT Specific in vivo association between the bHLH and LIM proteins implicated in human T cell leukemia
RL EMBO J. 13:4831-4839 (1994).
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