
AC   T01685
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ID   T01685
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DT   21.02.1996 (created); ewi.
DT   26.07.2011 (updated); jag.
CO   Copyright (C), QIAGEN.
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FA   ADA2
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SY   ADA2; ADA2-like protein; ADA2A; FLJ12705; hADA2; KL04P; TADA2A; TADA2L; transcriptional adapter 2; transcriptional adaptor 2 (ADA2 homolog, yeast)-like; transcriptional adaptor 2A.
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OS   human, Homo sapiens
OC   eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE   G013785 TADA2A; HGNC: TADA2A.
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HO   ADA2 (yeast).
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CL   C0022; trp; 3.5.1.6.1.
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SF   31% identity and 53% similarity with yeast ADA2 [1];
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FF   adaptor for acidic activators [1];
FF   can be functionally replaced by yeast ADA2 [1];
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IN   T05038 ADA3; human, Homo sapiens.
IN   T01686 GCN5; human, Homo sapiens.
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DR   TRANSPATH: MO000023594.
DR   UniProtKB: O75478; Q9UCW2.
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RN   [1]; RE0003820.
RX   PUBMED: 8552087.
RA   Candau R., Moore P. A., Wang L., Barlev N., Ying C. Y., Rosen C. A., Berger S. L.
RT   Identification of human proteins functionally conserved with the yeast putative adaptors ADA2 and GCN5
RL   Mol. Cell. Biol. 16:593-602 (1996).
RN   [2]; RE0047416.
RX   PUBMED: 12034840.
RA   Benecke A., Gaudon C., Garnier J. M., vom Baur E., Chambon P., Losson R.
RT   ADA3-containing complexes associate with estrogen receptor alpha.
RL   Nucleic Acids Res. 30:2508-2514 (2002).
RN   [3]; RE0064710.
RX   PUBMED: 15932940.
RA   Palhan V. B., Chen S., Peng G. H., Tjernberg A., Gamper A. M., Fan Y., Chait B. T., La Spada A. R., Roeder R. G.
RT   Polyglutamine-expanded ataxin-7 inhibits STAGA histone acetyltransferase activity to produce retinal degeneration.
RL   Proc. Natl. Acad. Sci. USA 102:8472-8477 (2005).
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