TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T01946 XX ID T01946 XX DT 18.11.1996 (created); ewi. DT 16.05.2016 (updated); mom. CO Copyright (C), QIAGEN. XX FA NFATc3 XX SY NF-AT4; NF-ATc3; NF-ATx; NFAT4; NFATx; Nuclear Factor of Activated T-cells x. XX OS human, Homo sapiens OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates XX GE G005445 NFATC3; HGNC: NFATC3. XX CL C0052; REL/NFAT; XX SF regions of high similarity with NF-ATp and NF-ATc in the N-terminal and central regions [1]; SF forms a ternary complex at the IL-2 enhancer with AP-1 [1]; XX CP highest level in thymus, much lower in leukocytes, testis, ovary, spleen, even lower in colon, muscle, kidney, prostate, small intestine [1]. CN brain, heart, pancreas [1]. XX FF transcription activating complex with AP-1 [1]; XX IN T17256 calcineurin; rat, Rattus norvegicus. IN T04640 SRC3; human, Homo sapiens. XX MX M01886 V$NFAT4_Q3. MX M07607 V$NFAT4_Q5. MX M08001 V$NFATC3_01. MX M00935 V$NFAT_Q4_01. MX M00302 V$NFAT_Q6. XX BS R23653. BS R69880. BS R69892. BS R69894. BS R27594. BS R05097. BS R72070. XX DR TRANSPATH: MO000020739. DR TRANSCOMPEL: C00161. DR TRANSCOMPEL: C00560. DR UniProtKB: Q12968; NFC3_HUMAN. XX RN [1]; RE0004632. RX PUBMED: 7739550. RA Masuda E. S., Naito Y., Tokumitsu H., Campbell D., Saito F., Hannum C., Arai K.-I., Arai N. RT NFATx, a novel member of the nuclear factor of activated T cells family that is expressed predominantly in the Thymus RL Mol. Cell. Biol. 15:2697-2706 (1995). RN [2]; RE0004633. RX PUBMED: 8240350. RA Tokumitsu H., Masuda E. S., Tsuboi A., Arai K.-I., Arai N. RT Purification of the 120 kDa component of the human nuclear factor of activated T cells (NF-AT): reconstitution of binding activity to the cis-acting element of the GM-CSF and IL-2 promoter with AP-1 RL Biochim. Biophys. Acta 196:734-744 (1993). XX //