AC T01946
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ID T01946
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DT 18.11.1996 (created); ewi.
DT 16.05.2016 (updated); mom.
CO Copyright (C), QIAGEN.
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FA NFATc3
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SY NF-AT4; NF-ATc3; NF-ATx; NFAT4; NFATx; Nuclear Factor of Activated T-cells x.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G005445 NFATC3; HGNC: NFATC3.
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CL C0052; REL/NFAT; 6.1.3.0.3.
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SF regions of high similarity with NF-ATp and NF-ATc in the N-terminal and central regions [1];
SF forms a ternary complex at the IL-2 enhancer with AP-1 [1];
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CP highest level in thymus, much lower in leukocytes, testis, ovary, spleen, even lower in colon, muscle, kidney, prostate, small intestine [1].
CN brain, heart, pancreas [1].
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FF transcription activating complex with AP-1 [1];
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IN T17256 calcineurin; rat, Rattus norvegicus.
IN T04640 SRC3; human, Homo sapiens.
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MX M01886 V$NFAT4_Q3.
MX M07607 V$NFAT4_Q5.
MX M08001 V$NFATC3_01.
MX M00935 V$NFAT_Q4_01.
MX M00302 V$NFAT_Q6.
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BS R23653.
BS R69880.
BS R69892.
BS R69894.
BS R27594.
BS R05097.
BS R72070.
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DR TRANSPATH: MO000020739.
DR TRANSCOMPEL: C00161.
DR TRANSCOMPEL: C00560.
DR UniProtKB: Q12968; NFC3_HUMAN.
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RN [1]; RE0004632.
RX PUBMED: 7739550.
RA Masuda E. S., Naito Y., Tokumitsu H., Campbell D., Saito F., Hannum C., Arai K.-I., Arai N.
RT NFATx, a novel member of the nuclear factor of activated T cells family that is expressed predominantly in the Thymus
RL Mol. Cell. Biol. 15:2697-2706 (1995).
RN [2]; RE0004633.
RX PUBMED: 8240350.
RA Tokumitsu H., Masuda E. S., Tsuboi A., Arai K.-I., Arai N.
RT Purification of the 120 kDa component of the human nuclear factor of activated T cells (NF-AT): reconstitution of binding activity to the cis-acting element of the GM-CSF and IL-2 promoter with AP-1
RL Biochim. Biophys. Acta 196:734-744 (1993).
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