TRANSFAC-Logo

TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN


AC T01967 XX ID T01967 XX DT 21.11.1996 (created); ewi. DT 19.08.2014 (updated); pro. CO Copyright (C), QIAGEN. XX FA LHX2 XX SY hLH-2; LH-2. XX OS human, Homo sapiens OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates XX GE G004093 LHX2; HGNC: LHX2. XX HO Ap (Drosophila) T01074. XX CL C0025; LIM-homeo; 3.1.5.3.1. XX FF able to regulate correctly target genes of Drosophila homolog T01074 in the fly, causes the same phenotypes when ectopically expressed, and rescues ap mutant phenotypes as efficiently as the fly protein [2]; FF aberrantly expressed in chronic myelogenous leukemia [1]; XX MX M01325 V$LHX2_01. MX M04385 V$LHX2_02. MX M07047 V$LHX2_Q4. MX M07385 V$LHX2_Q6. XX BS R63421. BS R19707. BS R63381. XX DR TRANSPATH: MO000026059. DR UniProtKB: P50458; XX RN [1]; RE0004753. RX PUBMED: 8649822. RA Wu H. K., Heng H., Siderovski D., Dong W., Okuno Y., Shi X., Tsui L., Minden M. RT Identification of a human LIM-Hox gene, hLH-2, aberrantly expressed in chronic myelogenous leukaemia and located on 9q33-34.1 RL Oncogene 12:1205-1212 (1996). RN [2]; RE0017735. RX PUBMED: 10051612. RA Rincon-Limas D. E., Lu C. H., Canal I., Calleja M., Rodriguez-Esteban C., Izpisua-Belmonte J. C., Botas J. RT Conservation of the expression and function of apterous orthologs in Drosophila and mammals. RL Proc. Natl. Acad. Sci. USA 96:2165-2170 (1999). XX //