AC T01074
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ID T01074
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DT 24.02.1994 (created); ewi.
DT 07.02.2006 (updated); vma.
CO Copyright (C), QIAGEN.
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FA Ap
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SY ap; Apterous.
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OS fruit fly, Drosophila melanogaster
OC eukaryota; animalia; metazoa; arthropoda; insecta; diptera; drosophiloidea; drosophilidae
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GE G018887 ap.
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HO Lhx2 (vertebrates) T01967 T01969.
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CL C0025; LIM-homeo.
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SZ 469 AA; 52.0 kDa (cDNA) (calc.).
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SQ MGVCTEERPVMHWQQSARFLGPGAREKSPTPPVAHQGSNQCGSAAGANNNHPLFRACSSS
SQ SCPDICDHSTKPFGNAYGTESFRSYETADRATFEDSAAKFSISRSRTDCTEVSDETTSGI
SQ SFKTEPFGPPSSPESTSDSKITRNLDDCSGCGRQIQDRFYLSAVEKRWHASCLQCYACRQ
SQ PLERESSCYSRDGNIYCKNDYYSFFGTRRCSRCLASISSNELVMRARNLVFHVNCFCCTV
SQ CHTPLTKGDQYGIIDALIYCRTHYSIAREGDTASSSMSATYPYSAQFGSPHNDSSSPHSD
SQ PSRSIVPTGIFVPASHVINGLPQPARQKGRPRKRKPKDIEAFTANIDLNTEYVDFGRGSH
SQ LSSSSRTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLSQKTGLPKRVLQVWFQNARA
SQ KWRRMMMKQDGSGLLEKGEGALDLDSISVHSPTSFILGGPNSTPPLNLD
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FT 89 461 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 146 207 
PS50023; LIM_DOMAIN_2.
FT 147 200 
SM00132; lim_4.
FT 148 206 
PF00412; LIM domain.
FT 208 270 
PS50023; LIM_DOMAIN_2.
FT 209 263 
SM00132; lim_4.
FT 210 269 
PF00412; LIM domain.
FT 365 425 
PS50071; HOMEOBOX_2.
FT 367 429 
SM00389; HOX_1.
FT 368 424 
PF00046; Homeobox domain.
FT 368 424 PS50558; LIM_HOMEODOMAIN.
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SF interaction with Chip T04201 mediated by the LIM domains [2];
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CP embryo: portions of PNS and CNS; larvae: imaginal discs, CNS; adult: imaginal discs, CNS [1].
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FF required for normal wing development and development of imaginal discs [1];
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IN T04201 Chip; fruit fly, Drosophila melanogaster.
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MX M02327 I$AP_01.
MX M01095 I$AP_Q6.
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BS R17998.
BS R17999.
BS R18000.
BS R18001.
BS R18003.
BS R18004.
BS R18005.
BS R18010.
BS R18014.
BS R18018.
BS R18019.
BS R18020.
BS R18021.
BS R18022.
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DR TRANSPATH: MO000025380.
DR EMBL: M92841;
DR EMBL: X65158;
DR UniProtKB: P29673;
DR FLYBASE: FBgn0000099; ap.
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RN [1]; RE0000775.
RX PUBMED: 1349545.
RA Cohen B., McGuffin E., Pfeifle C., Segal D., Cohen S. M.
RT apterous, a gene required for imaginal disc development in Drosophila encodes a member of the LIM family of developmental regulatory proteins
RL Genes Dev. 6:715-729 (1992).
RN [2]; RE0015594.
RX PUBMED: 9334334.
RA Morcillo P., Rosen C., Baylies M. K., Dorsett D.
RT Chip, a widely expressed chromosomal protein required for segmentation and activity of a remote wing margin enhancer in Drosophila
RL Genes Dev. 11:2729-2740 (1997).
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