AC T01992
AS T22667, T22669.
XX
ID T01992
XX
DT 06.12.1996 (created); ewi.
DT 19.02.2012 (updated); mkl.
CO Copyright (C), QIAGEN.
XX
FA Abd-A
XX
SY abdominal-A; CG10325; Homeobox protein abdominal-A.
XX
OS fruit fly, Drosophila melanogaster
OC eukaryota; animalia; metazoa; arthropoda; insecta; diptera; drosophiloidea; drosophilidae
XX
GE G018855 abd-A.
XX
CL C0006; homeo.
XX
SZ 330 AA; 36.2 kDa (gene) (calc.).
XX
SQ MYPYVSNHPSSHGGLSGMAGFTGLEDKSCSRYTDTVMNSYQSMSVPASASAQFAQFYQHA
SQ TAAASAVSAASAGAIGVDSLGNACTQPASGVMPGAGGAGGAGIADLPRYPWMTLTDWMGS
SQ PFERVVCGDFNGPNGCPRRRGRQTYTRFQTLELEKEFHFNHYLTRRRRIEIAHALCLTER
SQ QIKIWFQNRRMKLKKELRAVKEINEQARRDREEQEKMKAQETMKSAQQNKQVQQQQQQQQ
SQ QQQQQQQQQHQQQQQQPQDHHSIIAHNPGHLHHSVVGQNDLKLGLGMGVGVGVGGIGPGI
SQ GGGLGGNLGMMSALDKSNHDLLKAVSKVNS
XX
SC Swiss-Prot#P29555-2
XX
FT 136 196 
PS50071; HOMEOBOX_2.
FT 138 200 
SM00389; HOX_1.
FT 139 195 
PF00046; Homeobox domain.
XX
SF binds cooperatively with Exd to DNA [3];
XX
FF repressor through multiple binding sites [4];
FF may compete for binding to certain sites with the activator Antp in some neuronal cells [4];
FF homeotic selector gene product, required for normal development of abdominal structures;
XX
IN T01482 Exd; fruit fly, Drosophila melanogaster.
XX
MX M02324 I$ABDA_01.
MX M07753 I$ABDA_02.
MX M01083 I$ABDA_Q6.
XX
BS R09578.
BS R17739.
BS R17741.
BS R17744.
BS R17745.
BS R17749.
BS R17750.
BS R17753.
BS R17754.
BS R17757.
BS R17758.
BS R17760.
BS R17762.
BS R17765.
BS R17766.
BS R17768.
BS R17771.
BS R17772.
BS R17775.
BS R17776.
BS R17779.
BS R17780.
BS R17783.
BS R17784.
BS R17787.
BS R17788.
BS R17790.
BS R17916.
BS R17458.
BS R17461.
BS R17464.
BS R17471.
BS R17475.
BS R17477.
BS R17479.
BS R17482.
BS R17484.
BS R17332.
BS R17336.
BS R17339.
BS R17342.
BS R02507.
XX
DR TRANSPATH: MO000026075.
DR EMBL: L31790;
DR EMBL: X54453;
DR UniProtKB: P29555-2;
DR FLYBASE: FBgn0000014; abd-A.
XX
RN [1]; RE0004952.
RX PUBMED: 1358457.
RA Vachon G., Cohen B., Pfeifle C., McGuffin M. E., Botas J., Cohen S. M.
RT Homeotic genes of the Bithorax complex repress limb development in the abdomen of the Drosophila embryo through the target gene Distal-less
RL Cell 71:437-450 (1992).
RN [2]; RE0004953.
RX PUBMED: 1979297.
RA Karch F., Bender W., Weiffenbach B.
RT abdA expression in Drosophila embryos
RL Genes Dev. 4:1573-1587 (1990).
RN [3]; RE0004954.
RX PUBMED: 7915200.
RA van Dijk M. A., Murre C.
RT extradenticle raises the DNA binding specificity of homeotic selector gene products
RL Cell 78:617-624 (1994).
RN [4]; RE0004955.
RX PUBMED: 8096172.
RA Appel B., Sakonju S.
RT Cell-type-specific mechanisms of transcriptional repression by the homeotic gene products UBX and ABD-A in Drosophila embryos
RL EMBO J. 12:1099-1109 (1993).
RN [5]; RE0004956.
RX PUBMED: 7906203.
RA Capovilla M., Brandt M., Botas J.
RT Direct regulation of decapentaplegic by Ultrabithorax and its role in Drosophila midgut morphogenesis
RL Cell 76:461-475 (1994).
RN [6]; RE0015328.
RX PUBMED: 7902124.
RA Kalionis B., O'Farrell P. H.
RT A universal target sequence is bound in vitro by diverse homeodomains
RL Mech. Dev. 43:57-70 (1993).
XX
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