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TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN


AC T02015 XX ID T02015 XX DT 16.12.1996 (created); ewi. DT 08.12.2011 (updated); hna. CO Copyright (C), QIAGEN. XX FA En-1 XX SY Engrailed 1; Hu-en.1. XX OS human, Homo sapiens OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates XX GE G002103 EN1; HGNC: EN1. XX HO En (Drosophila) T00253. XX CL C0006; homeo; 3.1.2.7.1. XX CN embryo: cerebellum, frontal cortex, liver, lung [1]. XX MX M00396 V$EN1_01. MX M01365 V$EN1_02. MX M04316 V$EN1_07. MX M08912 V$EN1_09. XX BS R37434. XX DR TRANSPATH: MO000026095. DR UniProtKB: Q05925; XX RN [1]; RE0005045. RX PUBMED: 1363401. RA Logan C., Hanks M. C., Noble-Topham S., Nallainathan D., Provart N. J., Joyner A. L. RT Cloning and sequence comparison of the mouse, human, and chicken engrailed genes reveal potential functional domains and regulatory regions RL Dev. Genet. 13:345-358 (1992). RN [2]; RE0066482. RX PUBMED: 16571670. RA Bachar-Dahan L., Goltzmann J., Yaniv A., Gazit A. RT Engrailed-1 negatively regulates beta-catenin transcriptional activity by destabilizing beta-catenin via a glycogen synthase kinase-3beta-independent pathway. RL Mol. Biol. Cell 17:2572-2580 (2006). XX //