AC T02026
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ID T02026
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DT 19.12.1996 (created); hiwi.
DT 16.10.2009 (updated); pro.
CO Copyright (C), QIAGEN.
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FA C/EBPalpha(p30)
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SY C/EBPalpha(p30); C/EBPalpha-29(chicken); p30(C/EBPalpha); p30C/EBPalpha.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G000490 Cebpa.
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CL C0008; bZIP.
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SZ 242 AA; 25.6 kDa (cDNA) (calc.), 30 kDa (SDS) [2] [1]
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SQ MSAGAHGPPPGYGCAAAGYLDGRLEPLYERVGAPALRPLVIKQEPREEDEAKQLALAGLF
SQ PYQPPPPPPPPHPHASPAHLAAPHLQFQIAHCGQTTMHLQPGHPTPPPTPVPSPHAAPAL
SQ GAAGLPGPGSALKGLAGAHPDLRTGGGGGGSGAGAGKAKKSVDKNSNEYRVRRERNNIAV
SQ RKSRDKAKQRNVETQQKVLELTSDNDRLRKRVEQLSRELDTLRGIFRQLPESSLVKAMGN
SQ CA
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SC edited Swiss-Prot #P53566
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FT 164 228 SM00338; brlzneu.
FT 165 218 PF07716; Basic region leucine zipper.
FT 166 229 PS50217; BZIP.
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SF alternative translation initiation product is C/EBPalpha (p42 variant) T00104 [1] [2];
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CP (liver); A4 and WEHI 3BD cells [3].
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FF activator, less efficient than full-length C/EBPalpha since it lacks the main trans-activating domain [1];
FF in contrast to C/EBPalpha, it does not inhibit cell proliferation [1];
FF LPS also reduces levels of C/EBPalpha(p30) protein in liver, but raises that of a 20 kDa isoform probably due to shifting translation to another AUG codon [2];
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MX M00116 V$CEBPA_01.
MX M07037 V$CEBPA_Q4.
MX M01866 V$CEBPA_Q6.
MX M00159 V$CEBP_01.
MX M00201 V$CEBP_C.
MX M00190 V$CEBP_Q2.
MX M00912 V$CEBP_Q2_01.
MX M00770 V$CEBP_Q3.
MX M00249 V$CHOP_01.
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DR TRANSPATH: MO000026105.
DR EMBL: M62362;
DR UniProtKB: P53566;
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RN [1]; RE0003173.
RX PUBMED: 8415748.
RA Lin F.-T., MacDougald O.A., Diehl A.M., Lane M.D.
RT A 30-kDa alternative translation product of the CCAAT/enhancer binding protein alpha message: Transcriptional activator lacking antimitotic activity
RL Proc. Natl. Acad. Sci. USA 90:9606-9610 (1993).
RN [2]; RE0006628.
RX PUBMED: 8628296.
RA An M. R., Hsieh C.-C., Reisner P. D., Rabek J. P., Scott S. G., Kuninger D. T., Papaconstantinou J.
RT Evidence for posttranscriptional regulation of C/EBPalpha and C/EBPbeta isoform expression during the lipopolysaccharide-mediated acute-phase response
RL Mol. Cell. Biol. 16:2295-2306 (1996).
RN [3]; RE0034223.
RX PUBMED: 8855267.
RA Ford A. M., Bennett C. A., Healy L. E., Towatari M., Greaves M. F., Enver T.
RT Regulation of the myeloperoxidase enhancer binding proteins Pu1, C-EBP alpha, -beta, and -delta during granulocyte-lineage specification.
RL Proc. Natl. Acad. Sci. USA 93:10838-43 (1996).
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