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TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN


AC T02075 XX ID T02075 XX DT 29.01.1997 (created); ewi. DT 28.04.2011 (updated); jtr. CO Copyright (C), QIAGEN. XX FA Msx-2 XX SY Chox-8; Ghox-8; Hox-8; Hox-8.1; Quox-7. XX OS human, Homo sapiens OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates XX GE G006442 MSX2; HGNC: MSX2. XX HO Msh (Drosophila) T03551. XX CL C0006; homeo; 3.1.2.11.2. XX SF chromosomal location is closely linked to NKX2-5 T04323 [5]; XX CP placenta [4]. XX FF in adult bone cells, MSX2 expression is induced by 1,25-dihydroxyvitamin D3, but not by retinoic acid [3]; XX MX M01393 V$MSX2_01. MX M04407 V$MSX2_04. MX M03797 V$MSX2_Q3. MX M07425 V$MSX2_Q6. XX BS R35077. XX DR TRANSPATH: MO000026141. DR UniProtKB: P35548; XX RN [1]; RE0005161. RX PUBMED: 8106171. RA Jabs E. W., Mueller U., Li X., Ma L., Luo W., Hawoth I. S., Klisak I., Sparkes R., Warman M. L., Mulliken J. B., Snead M. l., Maxson R. RT A mutation in the homeodomain of teh human MSX2 gene in a family affected with autosomal dominant craniosynostosis RL Cell 75:443-450 (1993). RN [2]; RE0005162. RX PUBMED: 7687426. RA Suzuki M., Tanaka M., Iwase T., Naito Y., Sugimura H., Kino I. RT Over-expression of HOX-8, the human homologue of the mouse Hox-8 homeobox gene, in human tumors RL Biochem. Biophys. Res. Commun. 194:187-193 (1993). RN [3]; RE0005166. RX PUBMED: 8101453. RA Hodgkinson J. E., Davidson C. L., Beresford J., Sharpe P. T. RT Expression of a human homeobox-containing gene is regulated by 1,25(OH)2D3 in bone cells RL Biochim. Biophys. Acta 1174:11-16 (1993). RN [4]; RE0015321. RX PUBMED: 9073066. RA Quinn L. M., Johnson B. V., Nicholl J., Sutherland G. R., Kalionis B. RT Isolation and identification of homeobox genes from the human placenta including a novel member of the Distal-less family, DLX4 RL Gene 187:55-61 (1997). RN [5]; RE0015754. RX PUBMED: 7665173. RA Shiojima I., Komuro I., Inazawa J., Nakahori Y., Matsushita I., Abe T., Nagai R., Yazaki Y. RT Assignment of cardiac homeobox gene CSX to human chromosome 5q34 RL Genomics 27:204-206 (1995). XX //