AC T03551
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ID T03551
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DT 11.07.2000 (created); rio.
CO Copyright (C), QIAGEN.
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FA Msh
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SY muscle segment homeobox protein.
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OS fruit fly, Drosophila melanogaster
OC eukaryota; animalia; metazoa; arthropoda; insecta; diptera; drosophiloidea; drosophilidae
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HO Msx (vertebrates) T02071,T02072.
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CL C0006; homeo.
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SZ 515 AA; 54.3 kDa (cDNA) (calc.).
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SQ MLKLSPASMTVTGLRQTMTSPTVPPSTNTPAGNLIITSSSSNSGSNSGSNMSSGNMTSSN
SQ LTNLSPSHPAGLNALASPTSPSALLLAHQQHLLQQHQQHQQQQQQQQQAAALQLAAVHPP
SQ AHHLHKTTSRLSNFSVASLLADTRPRTPPNQAADGPQNLTSSAATSPISQASSTPPPPPA
SQ SAAAQVPANTFHPAAVAHHAHLLQAAHAAAAAHAQHQAMAAQLRQQQQQADARANSPPAS
SQ TSSTPSSTPLGSALGSQGNVASTPAKNERHSPLGSHTDSELEYDEEMLQDHEADHDEEED
SQ SIVDIEDMNADDSPRSTPDGLDGSGKSLESPHGPPPGSHMQSTILSPAALASGHVPIRPT
SQ PFSALAAAAVAWTGMGGGVPWPGTRQMPPFGPPGMFPGAGFGGDANEPPRIKCNLRKHKP
SQ NRKPRTPFTTQQLLSLEKKFREKQYLSIAERAEFSSSLRLTETQVKIWFQNRRAKAKRLQ
SQ EAEIEKIKMAALGRGAPGAQWAMAGYFHPSLMHLG
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SC translated from EMBL #U33319
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FT 46 356 PF00478; IMP dehydrogenase / GMP reductase domain.
FT 419 479 PS50071; HOMEOBOX_2.
FT 421 483 SM00389; HOX_1.
FT 422 478 PF00046; Homeobox domain.
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CP (stage 5:) dorsal lateral ectoderm, (stage 8:) ventral lateral ectoderm, (stage 9-12:) cell clusters in thoracic/abdominal segments, (stage 13:) CNS, lateral/dorsal mesoderm, somatic body wall muscles, (stage 15:) ventral nerve cord, brain [1].
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FF probably role in differentiation and patterning of embryonic muscles and mesoderm [1];
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MX M02306 I$DR_01.
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DR TRANSPATH: MO000027484.
DR EMBL: M38582;
DR EMBL: U33319;
DR UniProtKB: Q03372;
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RN [1]; RE0014767.
RX PUBMED: 7556942.
RA Lord P. C., Lin M. H., Hales K. H., Storti R. V.
RT Normal expression and the effects of ectopic expression of the Drosophila muscle segment homeobox (msh) gene suggest a role in differentiation and patterning of embryonic muscles
RL Dev. Biol. 171:627-640 (1995).
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