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TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN


AC T02080 XX ID T02080 XX DT 29.01.1997 (created); ewi. DT 30.09.2008 (updated); pwa. CO Copyright (C), QIAGEN. XX FA Otx1 XX SY orthodenticle related homeobox protein 1. XX OS mouse, Mus musculus OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae XX GE G006518 Otx1. XX HO Otd (Drosophila) T02078. XX CL C0006; homeo; 3.1.3.17.1. XX CP rostral brain: dorsal and most ventral regions of telencephalon, diencephalon, mesencephalon (day 10) [1]; 3,5 kb transcript from 10,5 dpc to 15,5 dpc mouse embryos; expression in the mesencephalon, diencephalon [4] [4] [1]. XX FF weak transcriptional activator [3]; XX MX M08892 V$CRX_Q6. MX M01366 V$OTX1_01. MX M04423 V$OTX1_06. MX M03838 V$OTX1_Q5. MX M01117 V$OTX_Q1. XX BS R15733. XX DR TRANSPATH: MO000026146. DR UniProtKB: P80205; XX RN [1]; RE0005031. RX PUBMED: 1353865. RA Simeone A., Acampora D., Gulisano M., Stornaiuolo A., Rambaldi M., Boncinelli E. RT Nested expression domains of four homeobox genes in developing rostral brain RL Nature 358:687-690 (1992). RN [2]; RE0005172. RX PUBMED: 8101484. RA Simeone A., Acampora D., Mallamaci A., Stornaiuolo A., D'Apice M. R., Nigro V., Boncinelli E. RT A vertebrate gene related to orthodenticle contains a homeodomain of the bicoid class and demarcates anterior neuroectoderm in the gastrulating mouse embryo RL EMBO J. 12:2735-2747 (1993). RN [3]; RE0015734. RX PUBMED: 9371841. RA Smidt M. P., van Schaick H. S., Lanctot C., Tremblay J. J., Cox J. J., van der Kleij A. A., Wolterink G., Drouin J., Burbach J. P. RT A homeodomain gene Ptx3 has highly restricted brain expression in mesencephalic dopaminergic neurons RL Proc. Natl. Acad. Sci. USA 94:13305-13310 (1997). RN [4]; RE0024916. RX PUBMED: 12055180. RA Zhang Y., Miki T., Iwanaga T., Koseki Y., Okuno M., Sunaga Y., Ozaki N., Yano H., Koseki H., Seino S. RT Identification, tissue expression, and functional characterization of Otx3, a novel member of the Otx family. RL J. Biol. Chem. 277:28065-28069 (2002). XX //