AC T02159
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ID T02159
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DT 26.05.1997 (created); hiwi.
DT 13.01.2010 (updated); pos.
CO Copyright (C), QIAGEN.
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FA TFIIB
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SY alpha; CB; CI; FA; factor e; general transcription factor IIB; GTF2B; TFIIB.
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OS rat, Rattus norvegicus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G014395 Gtf2b.
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CL C0030; histone fold.
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SZ 316 AA; 34.8 kDa (cDNA) (calc.).
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SQ MASTSRLDALPRVTCPNHPDAILVEDYRAGDMICPECGLVVGDRVIDVGSEWRTFSNDKA
SQ TKDPSRVGDSQNPLLSDGDLSTMIGKGTGAASFDEFGNSKYQNRRTMSSSDRAMMNAFKE
SQ ITTMADRINLPRNIVDRTNNLFKQVYEQKSLKGRANDAIASACLYIACRQEGVPRTFKEI
SQ CAVSRISKKEIGRCFKLILKALETSVDLITTGDFMSRFCSNLCLPKQVQMAATHIARKAV
SQ ELDLVPGRSPISVAAAAIYMASQASAEKRTQKEIGDIAGVADVTIRQSYRLIYPRAPDLF
SQ PSDFKFDTPVDKLPQL
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SC Swiss-Prot#P62916
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FT 1 296 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 119 200 
SM00385; cyclin_7.
FT 121 191 
PF00382; Transcription factor TFIIB repeat.
FT 213 294 
SM00385; cyclin_7.
FT 215 285 
PF00382; Transcription factor TFIIB repeat.
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IN T00108 C/EBPalpha-isoform1; rat, Rattus norvegicus.
IN T00372 HNF-4alpha1; rat, Rattus norvegicus.
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MX M08904 V$TFIIB_Q6_02.
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DR TRANSPATH: MO000046074.
DR EMBL: X65948; RNAINF.
DR UniProtKB: P62916;
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RN [1]; RE0005682.
RX PUBMED: 1620622.
RA Tsuboi A., Conger K., Garrett K. P., Conaway R. C., Conaway J. W., Arai N.
RT RNA polymerase II initiation factor Alpha from rat liver is almost identical to human TFIIB
RL Nucleic Acids Res. 20:3250-3250 (1992).
RN [2]; RE0005688.
RX PUBMED: 1692022.
RA Conaway R. C., Conaway J. W.
RT Transcription initiated by RNA polymerase II and purified transcription factors from liver. Transcription factors alpha, betagamma, and delta promote formation of intermediates in assembly of the functional preinitiation complex
RL J. Biol. Chem. 265:7559-7563 (1990).
RN [3]; RE0005691.
RX PUBMED: 2068101.
RA Conaway R. C., Garrett K. P., Hanley J. P., Conaway J. W.
RT Mechanism of promoter selection by RNA polymerase II: Mammalian transcription factors alpha and betagamma promote entry of polymerase into the preinitiation complex.
RL Proc. Natl. Acad. Sci. USA 88:6205-6209 (1991).
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