AC T02221
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ID T02221
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DT 23.10.1997 (created); ili.
CO Copyright (C), QIAGEN.
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FA Bro
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SY Brother.
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OS fruit fly, Drosophila melanogaster
OC eukaryota; animalia; metazoa; arthropoda; insecta; diptera; drosophiloidea; drosophilidae
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HO PEBP2beta, CBFbeta.
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SZ 177 AA; 20.9 kDa (cDNA) (calc.).
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SQ MPRVVPDQRSKFDSDELFRRLSRESEVRYTGYRERAMEERRMRFVNDCRKGYAEISMVAS
SQ GTNLQLYFNANHNPYAQEQDCDFERERGKVHLRSSFIMNGVCVRFRGWVDLDRLDGAACL
SQ DFDEQRAQQEDAQLQEQIQSYNQRMAESRRIYHTPQTPPEDHHHRGGPSLPRGPMGW
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SC Swiss-Prot#Q24039
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FT 1 170 PF02312; Core binding factor beta subunit.
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CN pole cells.
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FF enhances the DNA-binding activity of Runt [1];
FF region homologous to mammalian PEBP2beta is necessary for interaction with Runt [1];
FF the complexes formed with Bro and Runt are associated with a DNA bend of 61� [1];
FF expressed in embryogenesis of Drosophila [1];
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IN T01066 runt; fruit fly, Drosophila melanogaster.
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DR TRANSPATH: MO000026236.
DR EMBL: U22176;
DR UniProtKB: Q24039;
DR FLYBASE: FBgn0013755; Bro.
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RN [1]; RE0005912.
RX PUBMED: 8622696.
RA Golling G., Li L., Pepling M., Stebbins M., Gergen J. P.
RT Drosophila homologs of the proto-oncogene product PEBP2/CBFbeta regulate the DNA-binding properties of Runt
RL Mol. Cell. Biol. 16:932-942 (1996).
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