TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T02284 XX ID T02284 XX DT 18.11.1997 (created); ili. DT 07.01.2016 (updated); hna. CO Copyright (C), QIAGEN. XX FA ctcf XX SY CCCTC-binding factor. XX OS human, Homo sapiens OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates XX GE G013845 CTCF; HGNC: CTCF. XX CL C0001; CH; XX SF overall homology to chick ctcf T00172 [1]; XX CP HeLa cells [2]. XX FF Nuclear translocation is unaffected by N- or C- terminal deletions [2]; FF N-terminal domain is essential for APP transcription activity [2]; FF transcriptional repressor [1]; FF bind and repress c-myc promoters [1]; FF different combinations of zinc fingers are used to bind to divergent sequences within the c-myc promoters of different species [1]; XX IN T10378 Smad3; human, Homo sapiens. XX MX M01200 V$CTCF_01. MX M01259 V$CTCF_02. MX M02242 V$CTCF_03. MX M03895 V$CTCF_04. MX M04689 V$CTCF_05. MX M04727 V$CTCF_06. MX M04734 V$CTCF_07. MX M04745 V$CTCF_08. MX M04771 V$CTCF_10. MX M04824 V$CTCF_14. MX M08911 V$CTCF_15. MX M07249 V$CTCF_Q3_01. XX BS R23810. BS R04529. BS R58529. BS R60542. BS R32984. BS R20969. BS R24033. BS R24035. BS R22171. BS R22172. BS R26499. BS R60197. BS R60198. BS R71252. BS R24222. BS R24125. BS R62352. BS R63409. BS R67217. BS R67220. BS R59378. BS R67459. BS R67471. BS R67457. BS R67482. BS R23809. BS R60190. BS R60201. BS R60202. BS R32694. BS R32693. BS R32692. BS R32981. BS R32982. BS R32983. BS R24032. BS R23948. BS R21552. BS R21553. BS R21555. BS R21556. BS R24444. BS R24445. BS R62127. BS R23880. XX DR TRANSPATH: MO000046076. DR UniProtKB: P49711; CTCF_HUMAN. XX RN [1]; RE0006319. RX PUBMED: 8649389. RA Filippova G. N., Fagerlie S., Klenova E. M., Meyers C., Dehner Y., Goodwin G., Neiman P. E., Collins S. J., Lobanenkov V. V. RT An exceptionally conserved transcriptional repressor, CTCF, employs different combinations of zinc fingers to bind diverged promoter sequences of avian and mammalian c-myc oncogenes RL Mol. Cell. Biol. 16:2802-2813 (1996). RN [2]; RE0051281. RX PUBMED: 11706010. RA Vostrov A. A., Taheny M. J., Quitschke W. W. RT A region to the N-terminal side of the CTCF zinc finger domain is essential for activating transcription from the amyloid precursor protein promoter. RL J. Biol. Chem. 277:1619-1627 (2002). RN [3]; RE0053658. RX PUBMED: 17382889. RA Kim T. H., Abdullaev Z. K., Smith A. D., Ching K. A., Loukinov D. I., Green R. D., Zhang M. Q., Lobanenkov V. V., Ren B. RT Analysis of the vertebrate insulator protein CTCF-binding sites in the human genome. RL Cell 128:1231-1245 (2007). XX //