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AC T02304
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ID T02304
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DT 27.11.1997 (created); ili.
DT 05.09.2005 (updated); vma.
CO Copyright (C), QIAGEN.
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FA MAZ
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SY Myc-associated zinc finger protein; Pur-1; purine-binding transcription factor 1; SAF-1; serum amyloid A-activating factor.
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OS golden (Syrian) hamster, Mesocricetus auratus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; cricetidae; cricetinae; cricetini
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CL C0001; CH.
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SZ 331 AA; 33.4 kDa (cDNA) (calc.).
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SQ FPVLGLDSRGVGGLMNSFPPPQGHAQNPLQVGAELQSRFFASQGCAQSPFQAAPAPPPTP
SQ QAPAAEPLQVDLLPVLAAAQESAAAAAAAAAAAAAVVTAPPAPAAASTVDTAALKQPPAP
SQ PPPPPAVSAPAAEAAPPAAAATIAAAAATAVVAPTSTVAVAPVASVLEKKTKSKGPYICA
SQ LCAKEFKNGYNLRRHEAIHTGAKAGRVPSGAMKMPTMVPLSLLSVPQLSGASGGGGEAGA
SQ GGGTTAVAAGGVVTTTASGKRIRKNHACEMCGKAFRDVYHLNRHKLSHSDEKPYQCPVCQ
SQ QRFKRKDRMSYHVRSHDGAVHKPYNCSHCGK
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SC translated from EMBL #L06008
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FT 46 324
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 177 199
PF00096; zf-C2H2.
FT 177 199
SM00355; c2h2final6.
FT 177 204
PS50157; ZINC_FINGER_C2H2_2.
FT 266 288
PF00096; zf-C2H2.
FT 266 288
SM00355; c2h2final6.
FT 266 293
PS50157; ZINC_FINGER_C2H2_2.
FT 294 316
PF00096; zf-C2H2.
FT 294 316
SM00355; c2h2final6.
FT 294 321
PS50157; ZINC_FINGER_C2H2_2.
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SF protein sequence may be incomplete [2];
SF contains zinc fingers of C2H2 type [1];
SF homologous to the human factor MAZ T00490 and to T02303 in mouse [1];
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FF activator [1];
FF binds to purine-rich region (GAGA-box) in insulin and human islet amyloid polypeptide promoters [1];
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MX M07297 V$MAZ_Q5.
MX M00649 V$MAZ_Q6.
MX M02023 V$MAZ_Q6_01.
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BS R04630.
BS R04623.
BS R04624.
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DR TRANSPATH: MO000026304.
DR EMBL: L06008;
DR UniProtKB: P56670;
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RN [1]; RE0006397.
RX PUBMED: 1454839.
RA Kennedy G. C., Rutter W. J.
RT Pur-1, a zinc finger protein that binds to purine-rich sequences, transactivates an insulin promoter in heterologous cells
RL Proc. Natl. Acad. Sci. USA 89:11498-11502 (1992).
RN [2]; RE0006398.
RX PUBMED: 8449289.
RA Kennedy G. C., Rutter W. J.
RT Characterization of a cDNA encoding the insulin gene GAGA-binding factor, Pur-1
RL Biochem. Soc. Trans. 21:178-180 (1993).
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